FIG 1.

PapX and FocX share high sequence and structural homology. (A) Schematic of the pap1 and foc operons in CFT073. (B) The amino acid sequences of PapX and FocX were manually aligned, and residues in red signify differences in FocX compared to PapX. The predicted location of α-helices (blue) and β-sheets (red arrows) are shown above the amino acid sequence. (C) The predicted dimer structures of PapX (green) and FocX (blue) were created by using I-TASSER and aligned to the known structure of the dimer HucR by using Chimera (not shown). Amino acid differences between FocX and PapX are highlighted in red and labeled on one monomer.