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. 2018 Oct 12;7(11):5679–5690. doi: 10.1002/cam4.1824

Table 1.

Association between IL‐8 expression and clinicopathological characteristics in PDAC

Characteristics n IL‐8 expression in tumor IL‐8 expression in stroma
Low High P Low High P
Tumor size
≤3.0 cm 22 11 11 0.414 10 12 0.894
>3.0 cm 48 29 19 21 27
Histopathologic grade
Grade 1 23 13 10 0.624 12 11 0.564
Grade 2 25 16 9 11 14
Grade 3 22 11 11 8 14
T stage
T1/2 13 6 7 0.375 4 9 0.277
T3/4 57 34 23 27 30
Lymph nodes status
Negative 29 20 9 0.093 18 11 0.012*
Positive 41 20 21 13 28
Distant metastasis
Negative 58 34 24 0.583 26 32 0.841
Positive 12 6 6 5 7
CD68+ macrophages
Low 36 23 13 0.241 21 15 0.015*
High 34 17 17 10 24
CD163+ macrophages
Low 35 22 13 0.334 17 18 0.47
High 35 18 17 14 21
a

PDAC, pancreatic ductal adenocarcinoma.

*P < 0.05.