Figure 2.

miR‐144‐3p overexpression suppressed LUAD cell proliferation and invasion in vitro. A, The expression of miR‐144‐3p in four LUAD cell lines (NCI‐H1975, NCI‐H441, NCI‐H1792, and SPC‐A1) was lower than that in normal cell line BEAS‐2B. B, miR‐144‐3p mRNA expression in mimics group was much higher than that in NC group. At the same time, the expression level in inhibitor group was much lower than in that in NC group. C, Cell viability in mimics group was lower than that in NC group detected by MTT assay and the cell viability in inhibitor group was higher than that in NC group. D, It was verified that clone number was decreased by miR‐144‐3p mimics and increased by miR‐144‐3p inhibitor through clone formation assay. E, It was found that miR‐144‐3p mimics inhibited cell invasion but miR‐144‐3p inhibitor enhanced cell invasion through transwell assay. *P < 0.05, **P < 0.01, compared with NC group