Figure 6.

miR‐144‐3p inhibited NCI‐H1975 cells xenograft tumor growth in nude mice. A, miR‐144‐3p suppressed the growth of xenograft tumor volume in nude mice. B, miR‐144‐3p significantly decreased tumor weight in nude mice. Tumors were weighted on Day 42. C, D, qRT‐PCR analysis was used to detected miR‐144‐3p and EZH2 expression level in NC group and miR‐144‐3p mimics group. E, F, The results of Western blot and qRT‐PCR were verified that miR‐144‐3p downregulated VEGFA, MMP2, and MMP9 in mimics group. *P < 0.05, compared with NC group