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. 2018 Oct 16;7(11):5534–5542. doi: 10.1002/cam4.1697

Table 1.

Number of patients and median age at diagnosis (in years) of primary cancer and site of extranodal metastasis. Because patients may have several metastases, the sum of metastases is larger than that of patients

Primary cancer Male Female All
N Col % Median age at diagnosis N Col % Median age at diagnosis N Col % Median age at diagnosis
Upper aerodigestive 1718 2 63.8 791 1 65.6 2509 1 64.3
Esophagus 1770 2 66.1 489 1 69.6 2259 1 66.6
Stomach 4088 4 69.7 2484 3 71.2 6572 4 70.3
Colorectum 16 962 18 69.7 14 429 17 71.3 31 391 17 70.3
Liver 2524 3 69.4 3129 4 71.8 5653 3 70.7
Pancreas 4240 5 68.3 4121 5 70.3 8361 5 69.3
Lung 13 951 15 68.0 11 276 13 66.5 25 227 14 67.3
Breast 0 25 594 29 60.0 25 594 14 60.0
Other female genital 0 5867 7 67.3 5867 3 67.3
Ovary 0 6257 7 64.3 6257 3 64.3
Prostate 28 936 31 72.8 0 28 936 16 72.8
Kidney 4365 5 66.1 3000 3 68.9 7365 4 67.3
Bladder 3284 4 71.2 1157 1 72.9 4441 2 71.5
Melanoma 3015 3 63.3 1908 2 61.5 4923 3 62.6
Othera 7860 8 64.4 6366 7 67.8 14 226 8 66.1
All above 92 713 100 69.8 86 868 100 66.3 179 581 100 68.3
Location of metastasis ICD‐9 code ICD‐10 code Male Female All
N % of total N % of total N % of total
Lung 197.0 C78.0 19 191 15 22 931 16 42 122 15
Pleura 197.2 C78.2 3256 2 6729 5 9985 4
Other respiratory 197.1/3 C78.1/3 1786 1 1839 1 3625 1
Peritoneum 197.6 C78.6 5882 4 12 156 9 18 038 7
Liver 197.7 C78.7 32 160 24 34 346 24 66 506 24
Other G‐I 197.4‐5/8 C78.4‐5/8 4481 3 5591 4 10 072 4
Urinary system 198.0/1 C79.0/1 1746 1 1355 1 3101 1
Skin 1982 C79.2 1851 1 4037 3 5888 2
Nervous system 198.3/4 C79.3/4 11 890 9 13 965 10 25 855 9
Bone 198.5 C79.5 39 126 30 24 218 17 63 344 23
Ovary 198.6 C79.6 0 0 1395 1 1395 1
Adrenal gland 198.7 C79.7 2202 2 1769 1 3971 1
Other 198.8 C79.8 8335 6 11 099 8 19 434 7
Sum of all metastases 131 906 100 141 430 100 273 336 100
a

Other ICD‐7 codes 140‐209 except code 199 (cancer of unknown primary). Col%, percent distribution of patients. Other G‐I, other gastro‐intestinal location.