TABLE 1.

List of induced proteins by functional groups^a

Category and gene ID	Annotation	WT+RAD vs WT-RAD
		ΔRFP	ΔRNA	ΔTE
Protein folding/chaperones
LinJ.22.0670	A2 protein	+2.873	+0.576	+2.297
LinJ.33.0940	DnaJ, putative	+1.169	−0.241	+1.410
LinJ.27.2350	DnaJ, putative	+1.059	+0.550	+0.509
LinJ.25.2290	DnaJ/zinc-finger double-stranded RNA-binding, putative	+1.064	+0.813	+0.250
LinJ.29.1360	HSP100	+0.674	+0.301	+0.373
LinJ.34.0230	HSP23	+1.086	−0.495	+1.581
LinJ.28.3040	HSP70, putative	+1.024	−0.328	+1.352
LinJ.33.0350	HSP90	+1.601	+0.372	+1.230
LinJ.30.2480	mtHSP70	+1.535	+0.321	+1.215
LinJ.04.0710	Tir chaperone protein (CesT) family	−1.076	+0.431	−1.507
LinJ.36.2190	TPR repeat, putative	+1.027	+0.607	+0.420
LinJ.26.0360	TPR repeat, putative	−1.078	+0.000	−1.078
LinJ.05.0410	TPR repeat, putative	−1.160	−0.677	−0.483
Redox enzymes
LinJ.32.2880	As/Sb reductase, putative	+1.256	−0.919	+2.175
LinJ.34.0070	Ascorbate peroxidase, putative	+1.845	+0.481	+1.363
LinJ.31.2600	Ferredoxin, 2Fe-2S-like protein	+0.934	+0.122	+0.813
LinJ.27.0670	Glutaredoxin-like protein	+1.396	−0.241	+1.637
LinJ.26.0770	Glutathione peroxidase-like protein, putative	+2.512	+0.576	+1.936
LinJ.26.0780	Glutathione peroxidase-like protein, putative	+1.274	+0.582	+0.692
LinJ.32.1910	Iron superoxide dismutase, putative	+1.275	+0.010	+1.265
LinJ.23.0500	Trypanothione synthetase, putative	+1.207	−0.060	+1.268
LinJ.29.1250	Tryparedoxin 1	+1.170	+0.430	+0.740
LinJ.15.1140	Tryparedoxin peroxidase	+1.120	+0.235	+0.885
LinJ.15.1100	Tryparedoxin peroxidase	+1.029	+0.406	+0.623
Proteolytic enzymes
LinJ.26.2720	CAAX prenyl protease 2, putative	+1.270	+0.122	+1.148
LinJ.14.0920	Calpain-like cysteine peptidase, putative	+2.157	+0.247	+1.910
LinJ.20.1210	Calpain-like cysteine peptidase, putative	+1.067	+0.045	+1.023
LinJ.36.6520	Carboxypeptidase, putative	+1.700	+0.177	+1.523
LinJ.14.0180	Carboxypeptidase, putative	+1.051	+0.339	+0.712
LinJ.22.1540	Metallopeptidase, clan MA(E), family M3, putative, partial	+1.746	−0.475	+2.222
LinJ.36.4230	Metallopeptidase, clan MC, family M14, putative	+1.022	+0.268	+0.754
LinJ.09.1360	PPPDE putative peptidase domain-containing protein, putative	+1.369	−0.530	+1.900
LinJ.34.4390	Proteasome beta 7 subunit, putative	+2.134	−0.610	+2.745
LinJ.01.0730	Ubiquitin-activating enzyme, putative	+1.050	−0.129	+1.179
LinJ.28.0500	Ubiquitin-activating enzyme, putative	−1.348	−1.345	−0.003
LinJ.36.4580	Ubiquitin protein ligase, putative (fragment)	+1.256	−0.134	+1.390
LinJ.32.0730	Ubiquitin-conjugating enzyme E2, putative	+1.099	+0.759	+0.340
LinJ.21.0500	Ubiquitin-conjugating enzyme-like protein	+1.026	+0.278	+0.747
LinJ.31.1930	Ubiquitin-fusion protein	+2.716	+0.889	+1.826
LinJ.13.0620	Ubiquitin-like protein	+1.185	+0.145	+1.040
Amastin family
LinJ.30.1490	Ama1 protein, putative	+1.256	−0.521	+1.777
LinJ.08.0650	Amastin surface glycoprotein, putative	+1.058	+0.421	+0.637
LinJ.08.0780	Amastin-like protein	+2.157	+1.218	+0.938
LinJ.08.0680	Amastin-like protein	+2.104	+0.122	+1.983
LinJ.34.1040	Amastin-like protein	+2.078	+0.374	+1.704
LinJ.29.1450	Amastin-like protein	+1.513	+0.806	+0.706
LinJ.08.0760	Amastin-like protein	+1.034	+0.759	+0.275
LinJ.24.1300	Amastin-like surface protein-like protein	+2.597	−0.589	+3.186
LinJ.34.1680	Amastin-like surface protein, putative	+2.303	−0.241	+2.544
LinJ.34.1010	Amastin-like surface protein, putative	+1.809	+0.566	+1.242
LinJ.34.1020	Amastin-like surface protein, putative	+1.527	+0.264	+1.263
LinJ.34.1690	Amastin-like surface protein, putative	+1.349	−0.978	+2.327
LinJ.34.1730	Amastin-like surface protein, putative	+1.031	+0.185	+0.845
LinJ.34.1150	Amastin-like surface protein, putative	+1.015	+0.396	+0.619
LinJ.29.3010	Amastin, putative	+4.303	+0.049	+4.255
LinJ.29.3030	Amastin, putative	+2.283	+0.555	+1.727
LinJ.31.0460	Amastin, putative	+1.443	+0.213	+1.230
LinJ.29.3000	Amastin, putative	+1.157	+0.174	+0.983
Chromatin proteins
LinJ.20.0460	Cell cycle checkpoint protein RAD1-like, putative (fragment)	−1.481	−0.978	−0.503
LinJ.28.2550	DNA replication licensing factor MCM6, putative	−1.098	−1.148	+0.050
LinJ.09.0930	Histone H1-like protein	+1.041	+0.280	+0.761
LinJ.09.0930	Histone H1-like protein	+1.041	+0.280	+0.761
LinJ.27.1120	Histone H1, putative	+1.387	+0.377	+1.011
LinJ.27.1070	Histone H1, putative	+1.040	+0.096	+0.944
LinJ.27.1120	Histone H1, putative	+1.387	+0.377	+1.011
LinJ.27.1070	Histone H1, putative	+1.040	+0.096	+0.944
LinJ.29.1850	Histone H2A, putative	+5.007	+1.081	+3.927
LinJ.29.1870	Histone H2A, putative	+2.050	−0.759	+2.809
LinJ.29.1850	Histone H2A, putative	+5.007	+1.081	+3.927
LinJ.29.1870	Histone H2A, putative	+2.050	−0.759	+2.809
LinJ.19.0040	Histone H2B	+2.688	−0.796	+3.484
LinJ.09.1410	Histone H2B	+1.532	−0.493	+2.025
LinJ.19.0040	Histone H2B	+2.688	−0.796	+3.484
LinJ.09.1410	Histone H2B	+1.532	−0.493	+2.025
LinJ.16.0600	Histone H3, putative	+1.240	−0.505	+1.744
LinJ.16.0600	Histone H3, putative	+1.240	−0.505	+1.744
LinJ.36.0020	Histone H4	+1.443	−1.328	+2.771
LinJ.15.0010	Histone H4	+1.034	−0.210	+1.245
LinJ.35.0020	Histone H4, putative, pseudogene	+1.204	−0.108	+1.313
LinJ.30.1010	Histone-binding protein RBBP4, putative	−1.388	−1.463	+0.076
LinJ.26.0710	Regulator of chromosome condensation (RCC1) repeat, putative	+1.671	−0.189	+1.860
Protein kinases
LinJ.27.1680	Casein kinase I-like protein	−2.651	+0.022	−2.673
LinJ.29.2260	Cdc2-related kinase 10, putative	+1.231	+0.039	+1.191
LinJ.33.1930	Dual-specificity protein kinase, putative	+1.993	+0.929	+1.064
LinJ.35.4060	Protein kinase A catalytic subunit isoform 1	+1.335	+0.185	+1.149
LinJ.32.1350	Protein kinase domain-containing protein, putative	+1.619	+0.039	+1.580
LinJ.32.1350	Protein kinase domain-containing protein, putative	+1.619	+0.039	+1.580
LinJ.29.0380	Protein kinase-like protein	+1.267	+0.921	+0.346
LinJ.17.0440	Protein kinase, putative	+2.207	+0.451	+1.756
LinJ.35.4690	Protein kinase, putative	+1.256	−1.700	+2.957
LinJ.14.1510	Protein kinase, putative	+1.050	+0.633	+0.416
LinJ.19.0590	Protein kinase, putative	−1.191	−0.300	−0.891
LinJ.19.1510	Protein kinase, putative	−1.329	+0.344	−1.673
LinJ.19.1640	Protein kinase, putative	−1.651	−1.241	−0.410
LinJ.28.3240	Serine/threonine kinase, putative	+1.157	−0.978	+2.135
Fatty acid metabolism
LinJ.14.0770	Fatty acid elongase, putative	+1.934	−0.826	+2.760
LinJ.14.0710	Fatty acid elongase, putative	+1.083	−0.027	+1.109
LinJ.14.0720	Fatty acid elongase, putative	−1.124	+0.344	−1.468
LinJ.14.0750	Fatty acid elongase, putative	−1.236	−0.241	−0.995
LinJ.14.0670	Fatty acid elongase, putative	−1.622	+0.149	−1.771
LinJ.01.0520	Fatty acyl-CoA synthetase 2, putative	−1.918	−0.794	−1.124
LinJ.03.0220	Long-chain fatty acyl-CoA synthetase, putative	−1.482	−0.241	−1.241
LinJ.01.0540	Long-chain-fatty acid-CoA ligase, putative	−1.663	−0.014	−1.650

^aPositive numbers indicate log₂ increases, while negative numbers indicate log₂ decreases.