Figure 9.

Schematic diagram of preparation and function of enzyme‐loaded microreactor. i) Layer‐by‐layer assembly of poly(l‐lysine) (PLL)/poly(methacrylic acid)‐co‐(cholesteryl methacrylate) (PMAc) polymer, using silica particle template; ii) deposition of phenylalanine ammonia lyase‐loaded liposomes, iii) surface capping by layer‐by‐layerassembly of PMAc layer and poly(dopamine) (PDA), and iv) removal of core template, and v) enzymatic conversion of phenylalanine (Phe) to nontoxic trans‐cinnamic acid (t‐ca) by phenylalanine ammonia lyase (PAL)‐loaded microreactors above T _m of liposomes. Reproduced with permission.106 Copyright 2017, Wiley‐VCH.