Table 1.

Relationship between CTHRC1 expression and clinicopathologic parameters of colorectal cancer patients

Characteristics	Number of case	CTHRC1 expression				P value
		High (n = 52)	%	Low (n = 164)	%
Age (y)	216
<50	46	19	36.5	27	16.5	0.187
≥50	170	33	63.5	137	83.5
Gender
Male	130	30	57.7	100	61.0	0.746
Female	86	32	42.3	64	39.0
Tumor size
<5 cm	122	34	65.4	88	53.7	0.151
≥5 cm	94	18	34.6	76	46.3
Location
Colon	90	25	48.1	65	39.6	0.333
Rectum	126	27	51.9	99	60.4
Histologic grade
Well	10	2	3.8	8	4.9	0.101
Moderate	182	40	76.9	142	86.6
Poor	24	10	19.2	14	8.5
Depth of invasion
T1	2	1	1.9	1	0.6	0.463
T2	29	5	9.6	24	14.6
T3	185	46	88.5	139	84.8
Lymphatic metastasis
Absent	106	20	38.5	86	52.4	0.083
Present	110	32	61.5	78	47.6
Venous invasion
Absent	196	48	92.3	148	90.2	0.788
Present	20	4	7.7	16	9.8
Nervous invasion
Absent	210	50	96.2	160	97.6	0.632
Present	6	2	3.8	4	2.4
Tumor budding[Link]
Bd1&Bd2	114	63	54.8	51	45.2	0.022
Bd3	102	31	29.6	71	70.4
Distant metastasis
Absent	177	40	76.9	137	83.5	0.303
Present	39	12	23.1	27	16.5
Duke's stage
I and II	94	15	28.8	79	48.2	0.016
III and IV	122	37	71.2	85	51.8
Recurrence[Link]
Absent	164	36	69.2	128	79.0	0.062
Present	50	16	30.8	34	21.0

According to Ref. 18

Analyzed with Kaplan‐Meier method and the log‐rank test.

Statistical significances (P value < 0.05) marked in bold font.