Table 2.
HRs of different staging group and C‐indexes in SEER and FUSCC cohort
| Staging system | SEER cohort | FUSCC cohort | |
|---|---|---|---|
| 8th AJCC staging system | HR (95% CI) | HR 95% CI | |
| Stage I | T1N0M0 | / | / |
| Stage II | T2N0M0 | 1.53 (1.44‐1.63) | 1.89 (1.29‐2.77) |
| Stage III | T1‐3N1M0 + T3N0M0 | 3.23 (3.08‐3.40) | 4.82 (3.64‐6.39) |
| Stage IV | TanyNanyM1+T4N0‐1M0 | 18.36 (17.73‐19.03) | 27.66 (21.77‐35.14) |
| Modified 8th AJCC staging system | |||
| Stage Ia | T1N0M0 | / | / |
| Stage Ib | T2N0M0 | 1.53 (1.44‐1.63) | 1.89 (1.29‐2.77) |
| Stage II | T3N0M0 | 2.76 (2.61‐2.92) | 3.21 (2.27‐4.55) |
| Stage III | T1‐3N1M0 + T4N0M0 | 7.80 (7.19‐8.46) | 12.82 (9.08‐18.10) |
| Stage IV | TanyNanyM1 + T4N1M0 | 19.11 (18.44‐19.80) | 30.02 (23.54‐38.27) |
| T1N0M0 | / | / | |
| T2N0M0 | 1.53 (1.44‐1.63) | 1.89 (1.29‐2.77) | |
| T3N0M0 | 2.76 (2.61‐2.92) | 3.21 (2.27‐4.55) | |
| T1N1M0 | 5.68 (4.41‐7.33) | 8.29 (4.05‐16.96) | |
| T2N1M0 | 7.15 (5.93‐8.62) | 17.53 (9.67‐31.78) | |
| T3N1M0 | 9.44 (8.41‐10.60) | 12.93 (7.52‐22.23) | |
| T1‐3N1M0 | 8.14 (7.41‐8.94) | 12.46 (8.54‐18.19) | |
| T4N0M0 | 6.96 (5.97‐8.12) | 13.07 (6.84‐24.98) | |
| T4N1M0 | 18.84 (14.95‐23.74) | 69.14 (34.56‐138.33) | |
| TanyNanyM1 | 19.12 (18.46‐19.82) | 29.16 (22.81‐37.29) | |
| C‐indexes (stages II and IV patients) | |||
| 8th AJCC staging system | 0.764 (0.758‐0.769) | 0.779 (0.743‐0.815) | |
| Modified 8th AJCC staging system | 0.770 (0.765‐0.776) | 0.801 (0.765‐0.838) | |
CI, confidence interval; C‐index, concordance index; HRs, hazard ratios compared with T1N0M0.