Figure 5.

The Hh signaling pathway is involved in DHA‐induced inhibition of cell proliferation. A and B, CCK8 assay of SKOV3 and SKOV3‐IP cells was conducted following treatment with purmorphamine, DHA or a combination of DHA and purmorphamine for 48 h. C and D, SKOV3 and SKOV3‐IP cells were treated with GANT61, DHA, or a combination of DHA and GATN61 for 48 h, while controls were treated with DMSO. CCK8 assay was used to analyze cell viability of SKOV3 and SKOV3‐IP cells. *P < 0.05, **P < 0.01 and ***P < 0.001, vs the control group. ^# P < 0.05, ^## P < 0.01 and ^### P < 0.001, vs the purmorphamine group GANT61 groups