Table 1.
Comparison of clinical and pathological data according to tumor localization
| All patients | RCC | LCC | ||||||
| (n = 942) | (n = 456) | (n = 486) | ||||||
| n | % | n | % | n | % | P | ||
| Age (yr) | < 65 | 636 | 67.5 | 304 | 66.7 | 332 | 68.3 | 0.590 |
| ≥ 65 | 306 | 32.5 | 152 | 33.3 | 154 | 31.7 | ||
| Gender | Male | 511 | 54.2 | 250 | 54.8 | 261 | 53.7 | 0.730 |
| Female | 431 | 45.8 | 206 | 45.2 | 225 | 46.3 | ||
| Family history | No | 916 | 97.2 | 439 | 96.3 | 477 | 98.1 | 0.790 |
| Yes | 26 | 2.8 | 17 | 3.7 | 9 | 1.9 | ||
| Smoking status | No | 592 | 62.8 | 277 | 60.7 | 315 | 64.8 | 0.192 |
| Yes | 350 | 37.2 | 179 | 39.3 | 171 | 35.2 | ||
| Alcohol use status | No | 893 | 94.8 | 434 | 95.2 | 459 | 94.4 | 0.614 |
| Yes | 49 | 5.2 | 22 | 4.8 | 27 | 5.6 | ||
| Mode of surgery | Elective | 791 | 84 | 400 | 87.7 | 391 | 80.5 | 0.002 |
| Emergent | 151 | 16 | 56 | 12.3 | 95 | 19.5 | ||
| DM | No | 845 | 89.7 | 407 | 89.3 | 438 | 90.1 | 0.527 |
| Yes | 93 | 9.9 | 48 | 10.5 | 45 | 9.3 | ||
| HT | No | 717 | 76.1 | 344 | 75.4 | 373 | 76.7 | 0.329 |
| Yes | 223 | 23.7 | 112 | 24.6 | 111 | 22.8 | ||
| Histology | Adenocarcinoma | 779 | 82.7 | 356 | 78.1 | 423 | 87 | < 0.001 |
| Mucinous adenocarcinoma | 163 | 17.3 | 100 | 21.9 | 63 | 13 | ||
| Tumor grade | Well and moderately | 879 | 93.3 | 420 | 92.1 | 459 | 94.4 | 0.151 |
| Poorly | 63 | 6.7 | 36 | 7.9 | 27 | 5.6 | ||
| Tumor stage | II | 567 | 60.2 | 271 | 59.4 | 296 | 60.9 | 0.644 |
| III | 375 | 39.8 | 185 | 40.6 | 190 | 39.1 | ||
| pT stage | T1-2 | 133 | 14.1 | 57 | 12.5 | 76 | 15.6 | 0.267 |
| T3 | 752 | 79.8 | 374 | 82 | 378 | 77.8 | ||
| T4 | 57 | 6.1 | 25 | 5.5 | 32 | 6.6 | ||
| The number of removed lymph nodes | < 12 | 296 | 31.4 | 102 | 22.4 | 194 | 39.9 | < 0.001 |
| ≥ 12 | 646 | 68.6 | 354 | 77.6 | 292 | 60.1 | ||
| pN | N0 | 567 | 60.2 | 269 | 59 | 298 | 61.3 | 0.589 |
| N1 | 273 | 29 | 133 | 29.2 | 140 | 28.8 | ||
| N2 | 102 | 10.8 | 54 | 11.8 | 48 | 9.9 | ||
| PNI | Negative | 728 | 78.3 | 354 | 78.5 | 374 | 78.1 | 0.879 |
| Positive | 202 | 21.7 | 97 | 21.5 | 105 | 21.9 | ||
| LVI | Negative | 629 | 67.8 | 303 | 67.3 | 326 | 68.2 | 0.777 |
| Positive | 299 | 32.2 | 147 | 32.7 | 152 | 31.8 | ||
| Surgical margin | Negative | 928 | 98.5 | 449 | 98.5 | 479 | 98.6 | 0.096 |
| Positive | 8 | 0.8 | 6 | 1.3 | 2 | 0.4 | ||
| Adjuvant treatment | No | 208 | 22.1 | 94 | 20.6 | 114 | 23.5 | 0.293 |
| Yes | 734 | 77.9 | 362 | 79.4 | 372 | 76.5 | ||
| Adjuvant treatment regimen | 5-FU-based | 493 | 67.2 | 243 | 67.1 | 250 | 67.2 | 0.978 |
| Oxaliplatin-based | 241 | 32.8 | 119 | 32.9 | 122 | 32.8 | ||
| Completion rate of adjuvant treatment | 695 | 94.7 | 344 | 95 | 351 | 94.4 | 0.685 | |
| Tumor recurrence | No | 804 | 85.4 | 389 | 85.3 | 415 | 85.4 | 0.971 |
| Yes | 138 | 14.6 | 67 | 14.7 | 71 | 14.6 | ||
| Locoregional recurrence | 40 | 29 | 21 | 31.3 | 19 | 26.8 | 0.553 | |
| Systemic recurrence | 98 | 71 | 46 | 68.7 | 52 | 73.2 | ||
| Metastasectomy | 48 | 34.8 | 24 | 35.8 | 24 | 33.8 | 0.804 | |
| Status | Exitus | 95 | 9.1 | 51 | 11.2 | 44 | 9.1 | 0.278 |
| Alive | 847 | 90.9 | 405 | 88.8 | 486 | 90.9 | ||
| Median | Min-Max | Median | Min-Max | Median | Min-Max | |||
| Age (yr) | 58 | 19-94 | 57 | 19-89 | 58 | 21-94 | 0.141 | |
| Follow-up (mo) | 90 | 1-252 | 90 | 1-252 | 90 | 5-235 | ||
| mean | SD | mean | SD | mean | SD | |||
| Number of removed lymph nodes | 17.57 | 10.843 | 19.78 | 11.059 | 15.5 | 10.223 | < 0.001 | |
| Number of metastatic lymph nodes | 1.46 | 4.068 | 1.41 | 2.86 | 1.5 | 4.944 | 0.743 | |
DM: Diabetes mellitus; HT: Hypertension; Max: Maximum; Min: Minimum; LCC: Left colon cancer; LVI: Lymphovascular invasion; n: Number of patients; pN: Pathological lymph node stage; PNI: Perineural invasion; pT: Pathological tumor stage; RCC: Right colon cancer.