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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Semin Immunopathol. 2018 Aug 23;40(6):593–603. doi: 10.1007/s00281-018-0699-4

Fig. 2.

Fig. 2

Unique stimuli and consequences for anti-inflammatory phagocyte receptors in acute rejection versus CAV. a Ischemia-reperfusion (I/R) of the allograft may stimulate shedding of anti-inflammatory receptors(Y) on macrophages (MΦs), contributing to activation of T cells and B cells and neutrophils (PMNs) and acute rejection and delayed CAV. b Unknown stimuli during chronic rejection, including from events triggered acutely after transplant, may similarly lead to shedding of anti-inflammatory receptors and activation of features of CAV. EC endothelial cell, Mo monocyte, ICAM intercellular adhesion molecule