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Duration of hypoxia determines state of oxidative stress depending on plasma fatty acid (FA) supply. (A) The concentration of FAs supplied via blood (parameter FAblood) influences the threshold at which the system jumps in the state of high oxidative stress. (B) Exemplified by a plasma FA concentration of 1.1 mM, the duration of the hypoxia phase determines, which state the system reaches after reoxygenation, a low or high oxidative stress state, respectively.
