Table 1.

Approximate Peak Plasma Concentrations (Cmax) after Oral Caffeine Administration in Healthy Humans.

Dose	Sex	Cmax	Note	Reference
5 mg/kg	Men	10 mg/L		[54,59]
5 mg/kg	Men	9 mg/L	Young and elderly men.	[60]
250 mg	Men & Women	7 mg/L		[20]
500 mg	Men & Women	17.3 mg/L		[20]
200 mg	Men	3.4 mg/L		[61]
400 mg	Men	7.4 mg/L		[61]
400 mg	Men	9.1 mg/L		[62]
2 mg/kg	Men & Women	3 mg/L		[63]
4 mg/kg	Men & Women	7.5 mg/L		[63]
100 mg	Men	2.5 mg/L	Administered as coffee.	[64]