Fig. 2.

CMIP expression on renal biopsy specimens from patients with MCNS in a context of HIV infection. CMIP is induced in the podocytes of patients with idiopathic MCNS relapse (biopsy at the time of the first episode) (a), but it is expressed at only very low levels during remission (d). Two representative cases from patients with MCNS in a context of HIV infection are shown, displaying strong staining with anti-CMIP antibody (b, c). By contrast, immunohistochemical studies of CMIP levels revealed very weak signals on the glomeruli of patients with HIVAN (e, f). Scale bar, 50 μm