Table 1.
Baseline characteristics of patients at the time of MCNS diagnosis
| Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
|---|---|---|---|---|---|---|---|---|
| Sex | F | M | F | F | F | M | F | M |
| Age (years) | 33 | 66 | 42 | 50 | 47 | 56 | 33 | 20 |
| Ethnicity | African | Caucasian | Caucasian | African | African | Caucasian | African | African |
| HT | No | No | No | No | No | Yes | No | No |
| Time between HIV diagnosis and MCNS (yr) | 7 | 7 | 22 | 9 | 4 | 23 | 4 | 0 |
| CD4+ T-cell count at MCNS diagnosis (/mm3) | 1028 | 738 | 1027 | 918 | 413 | 811 | 450 | 480 |
| HIV viral load at MCNS diagnosis (copies/ml) | 8029 | 0 | 0 | 0 | 0 | 0 | 1019 | 47,263 |
| Previous history of opportunistic infection | No | No | No | Pneumocystosis | No | No | M.avium pulmonary infection | No |
| HBV infection | No | Yes | No | No | No | Yes | Yes | No |
| HCV infection | No | No | No | No | No | Yes | No | No |
| Proteinuria (g/24 h) | 6.3 | 12 | 3.86 | 14.8 | 11 | 3.33 | 3.37 | 9 |
| Serum albumine (g/L) | 9.5 | 24 | 29.5 | 12 | 8 | 29 | 20 | 7.7 |
| Serum creatinine (μmol/L) | 109 | 130 | 77 | 62 | 110 | 61 | 134 | 79 |
| AKI stage (KDIGO) | 1 | 1 | No | No | No | No | 2 | No |
| Hematuria (cells/ml) | 0 | 34,000 | 0 | 34,000 | 13,000 | 0 | 500,000 | 0 |
F female, M male, HT hypertension, NA data not available, MCNS Minimal Change Nephrotic Syndrome, AKI acute kidney injury