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. 2018 Nov 20;19:201. doi: 10.1186/s12881-018-0717-3

Table 1.

General characteristics of the included studies for TGF-β1 levels in T2DN in this meta-analysis

First author, year Country According to Case Control
UAER or UACR Mean SD N Mean SD N
Ju HB 2000 China Normoalbuminuria 35.02 6.7 14 23.95 8.01 15
Microalbuminuria 39.31 5.35 18 23.95 8.01 15
Macroalbuminuria 58.58 9.56 13 23.95 8.01 15
Wang YJ 2002 China Normoalbuminuria 147.03 22.57 34 136.97 37.96 35
Macroalbuminuria 170.65 18.74 31 136.97 37.96 35
Li WM 2004 China Normoalbuminuria 58.91 11.03 46 47.25 6.22 48
Macroalbuminuria 387.45 82.06 48 47.25 6.22 48
Li ZJ 2004 China Normoalbuminuria 146 22 36 131 36 40
Macroalbuminuria 172 19 44 131 36 40
Jiang ZL 2005 China Normoalbuminuria 428.3 43.7 29 412.5 58.4 35
Microalbuminuria 578.5 69.4 27 412.5 58.4 35
Macroalbuminuria 683.4 84.3 28 412.5 58.4 35
Li ZZ 2005 China Normoalbuminuria 41 15.57 27 10.04 5.33 18
Microalbuminuria 66.35 18.04 12 10.04 5.33 18
Macroalbuminuria 53.31 15.64 18 10.04 5.33 18
Zhou Y 2005 China Normoalbuminuria 31.12 12.39 30 29.4 10.62 30
Microalbuminuria 79.63 15.96 30 29.4 10.62 30
Macroalbuminuria 136.6 21.45 30 29.4 10.62 30
Jing CY 2005 China Normoalbuminuria 31.16 14.23 31 24.58 12.61 20
Microalbuminuria 48.2 18.3 25 24.58 12.61 20
Macroalbuminuria 62.12 21.3 23 24.58 12.61 20
Wei YS 2005 China NR 41.57 10.55 91 25.46 7.88 105
Li HP 2006 China Normoalbuminuria 147.02 20.57 108 131.96 3.84 120
Macroalbuminuria 170.64 17.72 132 131.96 3.84 120
Tao SP 2006 China Normoalbuminuria 147 23 28 132 36 25
Macroalbuminuria 172 18 34 132 36 25
Meng T 2006 China Normoalbuminuria 217.7 126 28 84.5 23.4 30
Microalbuminuria 288.2 109.4 24 84.5 23.4 30
Macroalbuminuria 345.5 118.2 22 84.5 23.4 30
Xie HF 2006 China Normoalbuminuria 42.1 9.3 60 35.9 8.1 30
Macroalbuminuria 61.8 11.2 45 35.9 8.1 30
Qian YX 2006 China Normoalbuminuria 146 22 48 131 36 60
Macroalbuminuria 172 19 23 131 36 60
Fu CX 2007 China Normoalbuminuria 36.2 8.8 34 34.4 8.2 35
Microalbuminuria 69.4 12.8 31 34.4 8.2 35
Du JW 2007 China Normoalbuminuria 179.16 13.13 20 68.47 31.75 19
Microalbuminuria 192.66 57.25 21 68.47 31.75 19
Macroalbuminuria 582.04 211.25 20 68.47 31.75 19
Zhang WJ 2007 China Normoalbuminuria 23.35 3.7 36 20.35 3.7 40
Microalbuminuria 41.31 4.3 45 20.35 3.7 40
Macroalbuminuria 55.28 6.8 45 20.35 3.7 40
Lai X 2007 China Normoalbuminuria 89.65 28.33 27 31.46 9.07 43
Microalbuminuria 121.02 32.36 21 31.46 9.07 43
Macroalbuminuria 211.69 69.83 17 31.46 9.07 43
Lin YH 2007 China Normoalbuminuria 97.24 18.6 19 58.36 13.72 23
Macroalbuminuria 136.75 23.48 24 58.36 13.72 23
Zhang SF 2007 China Microalbuminuria 21.188 20.87 15 6.99 18.57 18
Macroalbuminuria 13.64 19.44 16 6.99 18.57 18
Zhang WK 2008 China Normoalbuminuria 23.3 10.1 30 20.3 3.7 26
Microalbuminuria 41.3 4.2 38 20.3 3.7 26
Macroalbuminuria 88.2 6.8 32 20.3 3.7 26
Wang YP 2008 China Normoalbuminuria 35.4 7.1 44 32.5 6.8 35
Macroalbuminuria 68.2 12.5 32 32.5 6.8 35
Zhang SB 2008 China NR 121.5 37.2 36 55.2 16.8 30
Li QX 2008 China Normoalbuminuria 31.9 9.72 26 21.5 6.89 20
Microalbuminuria 49.6 14.78 23 21.5 6.89 20
Macroalbuminuria 70.3 26.48 18 21.5 6.89 20
Feng SJ 2008 China Normoalbuminuria 208.2 110 25 80.62 3.4 38
Microalbuminuria 293.3 118.5 23 80.62 3.4 38
Macroalbuminuria 263.5 108.2 18 80.62 3.4 38
Zhang HM 2008 China Normoalbuminuria 32.52 12.24 40
Microalbuminuria 43.61 20.37 48
Cao B 2009 China Normoalbuminuria 31.2 5.6 31 17.4 3.4 30
Microalbuminuria 54.9 7.8 34 17.4 3.4 30
Macroalbuminuria 78.2 10.3 30 17.4 3.4 30
Li QX 2009 China Normoalbuminuria 31.9 9.72 26 21.5 6.89 20
Microalbuminuria 49.6 14.78 23 21.5 6.89 20
Macroalbuminuria 70.3 26.48 18 21.5 6.89 20
Yang YZ 2010 China Normoalbuminuria 28.59 3.64 25 21.07 3.48 30
Macroalbuminuria 43.12 4.62 25 21.07 3.48 30
Feng LM 2010 China Normoalbuminuria 34.2 7.1 40 32.8 6.4 35
Macroalbuminuria 69.4 7.2 32 32.8 6.4 35
Wu YJ 2010 China NG 172.5 20.4 30 125.4 14.6 28
Ye CF 2010 China Normoalbuminuria 31.36 5.75 37 26.54 5.78 32
Macroalbuminuria 58.69 9.87 37 26.54 5.78 32
Huang JW 2010 China Normoalbuminuria 41.85 10.38 29 22.5 5.75 30
Microalbuminuria 79.51 44.95 32 22.5 5.75 30
Macroalbuminuria 118.15 59.38 28 22.5 5.75 30
Chen D 2011 China Normoalbuminuria 129.16 27.08 30 83.32 30.55 60
Microalbuminuria 162.97 98.58 30 83.32 30.55 60
Macroalbuminuria 563.46 122.67 30 83.32 30.55 60
Li QX 2011 China Normoalbuminuria 31.9 9.72 26 21.5 6.89 20
Microalbuminuria 49.6 14.78 23 21.5 6.89 20
Macroalbuminuria 70.3 26.48 18 21.5 6.89 20
Zhou ZX 2011 China Normoalbuminuria 33.12 8.16 50 32.98 7.83 50
Microalbuminuria 49.21 18.11 56 32.98 7.83 50
He Y 2012 China Normoalbuminuria 147.01 20.98 48 131.82 36.01 60
Macroalbuminuria 172.31 19.06 42 131.82 36.01 60
Zhang Y 2012 China NG 154.8 7.09 28 122.84 6.3 15
Du ZC 2013 China Normoalbuminuria 18.55 2.67 20 8.97 4.087 18
Microalbuminuria 19.04 2.87 20 8.97 4.087 18
Macroalbuminuria 18.12 3.17 21 8.97 4.087 18
Zhang WQ 2014 China Normoalbuminuria 30.3 4.42 32 24.52 2.81 23
Microalbuminuria 34.32 4.32 41 24.52 2.81 23
Macroalbuminuria 58.31 5.16 13 24.52 2.81 23
Liu S 2014 China Normoalbuminuria 76.8 3.1 30 29.6 2.5 30
Microalbuminuria 114.8 3.1 30 29.6 2.5 30
Macroalbuminuria 135.8 5.9 30 29.6 2.5 30
Bao HL 2014 China Microalbuminuria 75.4 9.2 33 71.2 11.1 36
Feng R 2015 China Normoalbuminuria 7.58 2.11 22 5.13 1.63 30
Microalbuminuria 11.89 3.33 29 5.13 1.63 30
Macroalbuminuria 24.62 6.62 35 5.13 1.63 30
Lv C 2015 China Normoalbuminuria 27.3 5.45 137 14.98 3.23 131
Microalbuminuria 51.8 5.72 122 14.98 3.23 131
Macroalbuminuria 72.97 6.05 68 14.98 3.23 131
Bi FC 2016 China Normoalbuminuria 5.61 2.08 21 1.79 1.64 20
Microalbuminuria 8.98 2.26 20 1.79 1.64 20
Macroalbuminuria 11.39 1.61 20 1.79 1.64 20

NR: not report