Table 3.
Clinical and biochemical parameters of study cohort after stratification into two groups based on their BMI
| Clinical and biochemical parameters | Control (n = 155) (mean ± SD) | Moderate obese (n = 207) (mean ± SD) | p-value | Extreme obese (n = 130) (mean ± SD) | p-value |
|---|---|---|---|---|---|
| Age (years) | 43.86 ± 14.54 | 50.45 ± 11.17 | < 0.005 | 42.57 ± 13.72 | 0.248 |
| Male / Female, n (%) | 76 (49) / 79 (51) | 91 (43.96) / 116 (56.03) | 0.394 | 47 (36.15) / 83 (63.84) | 0.031 |
| BMI kg/m2 | 24.09 ± 2.60 | 34.15 ± 2.69 | < 0.005 | 48.26 ± 11.94 | < 0.005 |
| FBG (mg/dL) | 120.58 ± 56.75 | 161.33 ± 69.77 | < 0.005 | 137.33 ± 72.41 | 0.029 |
| Triglycerides (mg/dL) | 100.00 ± 62.45 | 133.91 ± 66.23 | < 0.005 | 141.54 ± 94.87 | < 0.005 |
| LDL (mg/dL) | 115.25 ± 42.90 | 107.81 ± 37.11 | 0.078 | 117.62 ± 34.97 | 0.614 |
| Cholesterol (mg/dL) | 189.34 ± 134.62 | 176.86 ± 40.23 | 0.208 | 183.92 ± 41.72 | 0.659 |
| HDL (mg/dL) | 48.52 ± 14.13 | 45.78 ± 13.13 | 0.058 | 44.23 ± 12.00 | 0.007 |
| T2DM, n (%) | 56 (36.12) | 175 (84.54) | < 0.005 | 60 (46.15) | 0.092 |
| HTN, n (%) | 0 | 60 (28.98) | < 0.005 | 25 (19.23) | < 0.005 |
| CVD, n (%) | 0 | 34 (16.42) | < 0.005 | 13 (10) | < 0.005 |
Data with significant p-value (< 0.05) are shown in bold
BMI body mass index, FBG fasting blood glucose, LDL low density lipoprotein, HDL high density lipoprotein, T2DM type-2 diabetes mellitus, HTN hypertension, CVD cardiovascular disease