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. 2018 Nov 20;19:203. doi: 10.1186/s12881-018-0715-5

Table 4.

Allelic distribution of patient population after stratifying to moderate-obese and extreme-obese groups based on their BMI

Gene SNP Allele Control Moderate obese Model 1a Model 2b Extreme obese Model 1a Model 2b
OR 98.75%CI P value OR 98.75%CI p value OR 98.75%CI P value OR 98.75%CI p value
UCP1 rs1800592 A 227 271 Ref 172 Ref
G 83 143 1.44 1.96–2.18 0.026 1.52 0.95–2.46 0.027 88 1.39 0.88–2.21 0.067 1.39 0.88–2.23 0.072
rs10011540 T 283 382 Ref 245 Ref
G 27 32 0.87 0.44–1.73 0.633 1.01 0.46–2.23 0.967 15 0.64 0.28–1.48 0.183 0.58 0.25–1.37 0.113
rs3811791 T 298 378 Ref 246 Ref
C 12 36 2.36 1.0–5.56 0.011 2.89 1.08–7.73 0.007 14 1.41 0.52–3.86 0.390 1.32 0.47–3.71 0.494
NPC1 rs1805081 T 275 371 Ref 234 Ref
C 35 43 0.91 0.50–1.66 0.698 0.78 0.39–1.56 0.376 26 0.87 0.44–1.73 0.619 0.86 0.43–1.75 0.612
rs1805082 T 225 306 Ref 185 Ref
C 85 108 0.93 0.61–1.42 0.688 0.91 0.56–1.49 0.637 75 1.07 0.67–1.71 0.705 1.04 0.65–1.68 0.813

Data with significant p-value (< 0.0125) are shown in bold

aUnadjusted and bAdjusted for Age, Gender and T2DM