Table 2.
PTSD Symptoms, Mood, and HRQoL in Patients at Baseline and 6-Month Follow-up.a
| Measure | Baseline, Mean (SD) | Six Months |
P Value | |
|---|---|---|---|---|
| Mean (SD) | Mean Difference (95% CI) | |||
| PCL-C PTSD total score | 19.5 (1.7) | 26.7 (8.3) | −7.2 (−9.0, −5.4) | <.0005 |
| HADS Depression score | 5.8 (1.04) | 5.9 (1.4) | −0.12 (−0.38, 0.13) | .349 |
| HADS Anxiety score | 6.4 (1.8) | 7.9 (4.1) | −1.7 (−2.6, −0.81) | <.0005 |
| Distress Thermometer | 2.8 (0.8) | 3.4 (1.2) | −0.64 (−0.91, −0.37) | <.0005 |
| Global quality of life | 70.2 (16.9) | 67.4 (15.8) | 4.2 (0.96, 7.5) | .012 |
| Physical function | 92.5 (11.5) | 86.8 (14.0) | 5.9 (2.5, 9.4) | .001 |
| Role function | 94.6 (11.3) | 86.4 (14.9) | 9.1 (6.1, 12.1) | <.0005 |
| Emotional function | 92.4 (10.1) | 89.3 (10.9) | 3.6 (1.4, 5.7) | .002 |
| Cognitive function | 98.6 (4.7) | 96.9 (6.5) | 2.0 (0.59, 3.4) | .006 |
| Social function | 70.6 (10.5) | 72 (10.3) | 0.22 (−1.4, 1.8) | .784 |
| Fatigue | 29.3 (13.6) | 32.4 (14.8) | −2.2 (−4.9, 0.50) | .108 |
| Nausea or vomiting | 5.4 (11.6) | 12.4 (15.3) | −6.0 (−9.2, −2.8) | <.0005 |
| Pain | 18.8 (18.8) | 19.3 (20.0) | −1.1 (−4.8, 2.6) | .551 |
| Dyspnea | 12.5 (18.3) | 14.2 (19.9) | −2.2 (−7.5, 3.0) | .402 |
| Insomnia | 12.9 (18.4) | 18.2 (21.4) | −6.2 (−10.7, −1.7) | .007 |
| Appetite loss | 26.5 (15.2) | 23.1 (15.5) | 2.2 (−4.0, 4.8) | .096 |
| Constipation | 26.9 (29.1) | 36 (31.8) | −7.5 (−12.2, −2.9) | .002 |
| Diarrhea | 0.35 (3.45) | 0 (0) | 0.44 (−0.44, 1.3) | .321 |
| Financial problems | 32.3 (7.69) | 32.4 (10.9) | −0.44 (−2.4, 1.5) | .658 |
Abbreviations: PTSD, posttraumatic stress disorder; HRQoL, health-related quality of life; PCL-C, PTSD Checklist Civilian Version (scored out of 85 points); HADS, Hospital Anxiety and Depression Scale.
a
Higher scores on the PCL-C PTSD, HADS Depression, HADS Anxiety, Distress Thermometer, and symptom domains represent worse status. Lower scores on the global quality of life and function domains represent worse status. Change over time data are shown for n =75, with repeated measures.