Table 2.
Regulation of Chinese Herbal Medicine in miRNA Expression and Function.
| Chinese Herbal Medicine | Active Compound | Type of Compound | miRNA | miRNA Expression | Function | Reference |
|---|---|---|---|---|---|---|
| Cordyceps militaris | Cordycepin | Adenosine analogue | miRNA-21 | Down | Antitumor | Yang et al33 |
| Tripterygium wilfordii | Triptolide | Diterpenoid epoxide | miRNA-137 | Up | Anti-glomerulosclerosis | Han et al40 |
| Ampelopsis grossedentata | Dihydromyricetin | Flavonoid | miRNA-34a | Down | Anti-brain aging | Kou et al37 |
| Radix Astragali | Calycosin | Isoflavone | miRNA-375 | Up | Neuroprotection | Wang et al36 |
| Radix puerariae | Puerarin | Isoflavone | miRNA-22 | Down | Cardiomyogenesis | Wang et al38 |
| Polygonum cuspidatum | Resveratrol | Polyphenol | miRNA-155 | Down | Anti-inflammation | Ma et al34 |
| Salvia miltiorrhiza | Salvianolic acid A | Polyphenol | miRNA-101 | Up | Recovery of neurological function | Yu et al35 |
| Salvia miltiorrhiza | Tanshinone IIA | Quinone | miRNA-133 | Up | Treatment of cardiovascular disorders | Zhang et al39 |
| Panax ginseng | Ginsenoside Rb1 | Saponine | miRNA-25 | Down | Antitumor | Li et al32 |