Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
LS mean change from baseline in DAS28-4 (ESR) through: (a) Month 6 in ORAL Sync (FAS, longitudinal model); (b) Month 12 in ORAL Sync by treatment sequence (FAS, longitudinal model); and (c) Month 48 in ORAL Sequel (FAS, no imputation). *P < 0.05; †P < 0.001; ‡P < 0.0001. BID: Twice daily; DAS28-4 (ESR): Disease Activity Score in 28 joints using erythrocyte sedimentation rate; FAS: Full analysis set; LS: Least squares; SE: Standard error.
