Table 1.
Baseline characteristics of the overall cohort.
| Overall cohort (n=380) | |
|---|---|
| Demographic and clinical characteristics | |
|
| |
| Age at enrollment, years (IQR) | 34 (31-37) |
| CRP∗, μg/mL (IQR) | 3.25 (1.61-8.07) |
| Ethnicity | |
| Caucasian, n (%) | 342 (90.7) |
| Latin American, n (%) | 20 (5.3) |
| African, n (%) | 6 (1.6) |
| Indian, n (%) | 9 (2.4) |
| BMI§, kg/m2 (IQR) | 21.19 (19.82-26.63) |
| Underweight, n (%) | 22 (9.2) |
| Normal weight, n (%) | 176 (73.6) |
| Overweight, n (%) | 37 (15.5) |
| Obese, n (%) | 10 (4.1) |
| Weight gain at delivery, kg (IQR) | 12 (10-15) |
|
| |
| Comorbidities | |
|
| |
| Thyroid disease, n (%) | 28 (7.4) |
| Hypertension, n (%) | 8 (2.1) |
| PCOS¥, n (%) | 7 (1.8) |
| Coagulation/PLTΦ diseases, n (%) | 8 (2.1) |
| Autoimmune diseases, n (%) | 35 (9.2) |
| GDM#, n (%) | 45 (11.9) |
|
| |
| Therapy | |
|
| |
| Thyroid hormone replacement therapy, n (%) | 27 (7.1) |
| Corticosteroid hormone, n (%) | 9 (2.4) |
| Aspirin, n (%) | 16 (4.2) |
|
| |
| Pregnancy and delivery characteristics | |
|
| |
| Gestational hypertension, n (%) | 5 (1.3) |
| Premature delivery, n (%) | 32 (9.4) |
| Cesarean delivery, n (%) | 177 (50.6) |
| Urgent Cesarean delivery, n (%) | 40 (11.4) |
| Gestational age at delivery, days (IQR) | 275 (270-282) |
| Overall maternal adverse outcomes | 189 (49.7) |
|
| |
| Baby characteristics | |
|
| |
| Baby weight, g (IQR) | 3280 (2948.75-3571.25) |
| Baby length, cm (IQR) | 49 (48-50) |
| Small for gestational age, n (%) | 74 (22.4) |
| Large for gestational age, n (%) | 23 (6.9) |
| Ponderal index (IQR) | 2.75 (2.56-2.94) |
| Macrosomy, n (%) | 10 (2.9) |
| Apgar score | |
| 0, n (%) | 1 (0.3) |
| 3, n (%) | 1 (0.3) |
| 4, n (%) | 1 (0.3) |
| 5, n (%) | 1 (0.3) |
| 6, n (%) | 1 (0.3) |
| 7, n (%) | 2 (0.6) |
| 8, n (%) | 4 (1.2) |
| 9, n (%) | 23 (6.8) |
| 10, n (%) | 306 (90) |
| Resuscitation, n (%) | 6 (1.7) |
| Fetal distress/polyhydramnios, n (%) | 3 (0.8) |
| Overall neonatal adverse outcomes, n (%) | 173 (45.5) |
| Maternal and neonatal adverse outcomes, n (%) | 272 (71.6) |
Data are expressed as median (interquartile range [IQR], number [n], or percentage [%]).
∗ CRP: C-reactive protein.
§ BMI: body mass index.
¥ PCOS: polycystic ovary syndrome.
Φ PLT: platelets.
# GDM: gestational diabetes mellitus.