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. 2018 Nov 20;16:139. doi: 10.1186/s12915-018-0609-1

Fig. 3.

Fig. 3

Summary of adenine base-editing results in zebrafish. a The base conversion efficiency, cleavage activities, indels frequency, and germline-targeting efficiency of five target sites (ddx17-g1, rps14, atp5b, wu:fc01d11 and musk) are summarized. b, c The sequence chromatograms results of zABE6.3, zABE7.8, and zABE7.9 in the rps14 and musk target site. Target sequence (black), PAM region (blue), and the substituted bases (red) are indicated. The red arrows indicate the overlapped peaks