Table 1.
Retrospective case–control study | ||||||||
---|---|---|---|---|---|---|---|---|
Study | Diagnosis | Cases (n) | PMR cases (n) | Controls (n) | PMR controls (n) | Odds ratio (95% CI) | Case rate (%) | Control rate (%) |
Anderson et al. [64] | Lymphoid malignancies | 33,721 | 344 | 122,531 | 1244 | 0.9 (0.8–1.0) | 1.02 | 1.02 |
Anderson et al. [63] | Myeloid malignancy | 9998 | 125 | 160,086 | 1288 | 1.7 (1.4–2.1) | 1.25 | 0.80 |
Myelodysplastic malignancy | 3758 | 55 | 42,886 | 518 | 1.5 (1.1–2) | 1.46 | 1.21 | |
Anderson et al. [67] | HCL | 418 | 9 | 160,086 | 2721 | 1.5 (0.5–3.9) | 2.15 | 1.70 |
Askling et al. [62] | All lymphoma | 42,676 | 114 | 78,487 | 250 | 0.8 (0.7–1.0) | 0.27 | 0.32 |
NHL | 28,355 | 88 | 52,164 | 187 | 0.9 (0.7–1.1) | 0.31 | 0.36 | |
HL | 4037 | 3 | 7394 | 15 | 0.4 (0.1–1.3) | 0.07 | 0.2 | |
CLL | 10,555 | 24 | 19,391 | 52 | 0.8 (0.5–1.4) | 0.23 | 0.27 | |
Kristinsson et al. [66] | Any MPN | 11,039 | 46 | 43,550 | 104 | 1.7 (1.2–2.5) | 0.42 | 0.24 |
Lanoy and Engels [65] | Cutaneous NHL | 2652 | 19 | 178,452 | 1731 | 0.7 (0.5–1.1) | 0.72 | 0.97 |
Lindqvist et al. [68] | MM | 19,112 | 56 | 75,408 | 116 | 1.9 (1.4–2.6) | 0.29 | 0.15 |
MGUS | 5403 | 58 | 21,209 | 79 | 2.9 (2.1–4.1) | 1.07 | 0.37 |
PMR polymyalgia rheumatica, HCL hairy cell leukaemia, NHL non-Hodgkin’s lymphoma, HL Hodgkin’s lymphoma, CLL chronic lymphocytic leukaemia, MM multiple myeloma, MPN myeloproliferative neoplasm, MGUS monoclonal gammopathy of undetermined significance