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. 2018 Aug 28;96(11):4768–4779. doi: 10.1093/jas/sky338

Table 6.

Effects of feeding sows diets supplemented with lysozyme on serum immunoglobulin and cytokines of sows and piglets1

Treatment
Item Control LZM 150 LZM 300 SEM P-value
Sows2
Day 1 of lactation
 IgA (mg/mL) 3.85 4.21 4.23 0.08 0.06
 IgG (mg/mL) 0.64 0.86 0.87 0.04 0.05
 IgM (mg/mL) 0.81b 1.01a 0.98a 0.03 <0.01
 IL-6 (ng/L) 58.41 56.48 56.08 2.06 0.90
 IL-10 (ng/L) 250.78 280.4 274.06 5.82 0.08
 TNF-α (ng/L) 122.68 119.54 121.1 2.26 0.86
Day 7 of lactation
 IgA (mg/mL) 4.31b 4.72a 4.70a 0.07 0.01
 IgG (mg/mL) 0.60 0.69 0.72 0.02 0.08
 IgM (mg/mL) 0.89 0.89 0.93 0.02 0.09
 IL-6 (ng/L) 67.09 63.88 63.58 0.91 0.23
 IL-10 (ng/L) 266.67b 287.36a 284.09a 3.50 0.02
 TNF-α (ng/L) 123.38 119.54 121.65 3.6 0.98
Day 21 of lactation
 IgA (mg/mL) 4.54 4.81 4.89 0.15 0.62
 IgG (mg/mL) 0.60 0.65 0.66 0.02 0.57
 IgM (mg/mL) 0.74b 0.85a 0.91a 0.02 0.05
 IL-6 (ng/L) 72.91 70.70 71.17 1.24 0.76
 IL-10 (ng/L) 235.84 251.11 250.36 3.89 0.20
 TNF-α (ng/L) 107.76 108.13 106.69 1.98 0.95
Piglets3
Day 21 of lactation
 IgA (mg/mL) 2.16b 2.62a 2.56a 0.07 0.01
 IgG (mg/mL) 2.25b 2.77a 2.65a 0.08 <0.01
 IgM (mg/mL) 23.98b 27.62a 28.87a 0.06 0.04
 IL-6 (ng/L) 52.82 50.70 50.77 0.64 0.34
 IL-10 (ng/L) 209.60b 256.59a 239.21a 6.96 0.01
 TNF-α (ng/L) 54.42 51.79 51.59 1.32 0.66

1LZM 150 = control diet + lysozyme 150 g/t, LZM 300 = control diet + lysozyme 300 g/t, IgA = immunoglobulin A, IgG = immunoglobulin G, IgM = immunoglobulin M, IL-6 = interleukin-6, IL-10 = interleukin-10, TNF-α = tumor necrosis factor-α.

2Data are means of 8 sows.

3Data are means of 8 piglets from 8 sows.

a,bWithin a row, means with different superscripts are different (P < 0.05).