Table-1.
Parameters | Group I control | Group II positive control | Group III treatment control | Group IV treatment group | ||||
---|---|---|---|---|---|---|---|---|
45th day of study | 90th day of study | 45th day of study | 90th day of study | 45th day of study | 90th day of study | 45th day of study | 90th day of study | |
Body weight (g) | 240±11.7 | 309.16±10.2 | 262.83±13.34 | 393.33±21.6a | 242.33±9.47 | 325±13.4b | 245±17.8 | 383.3±43.7ac |
TEC (million/mm3) | 5.78±0.9 | 6.30±0.2 | 6.6±0.45 | 6.83±1.3 | 6.41±0.30 | 6.7±0.5 | 7±0.60 | 7.46±1.02 |
TLC (xmm3 µl) | 8.81±1.12 | 10.22±0.58 | 12.4±0.76 | 16.3±0.73 | 9.16±3.7 | 10.9±0.62 | 10.9±0.4 | 10.5±1.05 |
PCV (%) | 34.6±5.7 | 37.83±1.3 | 39.6±2.6 | 32.5±2.1 | 38.5±1.8 | 37.83±1.7 | 40.5±3.4 | 41.3±1.2 |
Hb (g%) | 11.55±1.92 | 12.61±0.4 | 13.2±0.8 | 10.8±0.7 | 12.83±0.6 | 12.61±0.5 | 13.5±1.15 | 13.7±0.4 |
TC (mg/dl) | 46.03±7.8 | 50.67±7.04 | 113.58±11.75a | 155.3±10.58a | 48.75±2.75b | 46.06±4.27b | 99.0±6.9abc | 83.8±4.1abc |
TGs (mg/dl) | 68.70±50.0 | 67.17±11.08 | 150.58±33.27a | 178.2±39.84a | 57.43±9.14b | 67.83±34.93b | 122.1±17.6abc | 115.8±21.0abc |
LDL-C (mg/dl) | 17.44±4.7 | 20.13±2.78 | 64.88±5.86a | 95.9±9.10a | 16.31±2.85b | 17.45±4.69b | 30.4±2.9abc | 28.9±2.4abc |
Mean value of VLDL-C (mg/dl) | 10.45±1.8 | 13.43±2.22 | 21.12±6.65a | 31.0±8.78a | 11.49±1.83b | 11.65±5.32b | 17.4±3.5a | 14.2±4.2b |
HDL-C (mg/dl) | 28.16±2.8 | 27.10±5.15 | 17.58±5.35a | 18.4±3.96a | 29.95±2.93 | 28.96±3.02 | 22.2±2.4 | 21.7±2.6 |
Values are mean±SD, n=6. Values with different superscripts differ significantly (p<0.05) from the normal control or HCD or flaxseed control. TC=Total cholesterol, Hb=Hemoglobin, TGs=Triglycerides, VLDL-C=Very low-density lipoprotein cholesterol, TEC=Total erythrocyte count, PCV=Packed cell volume, TLC=Total leukocyte count, HDL-C=High-density lipoprotein cholesterol