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. Author manuscript; available in PMC: 2018 Nov 21.
Published in final edited form as: J Pediatr Surg. 2017 Jul 14;53(4):708–717. doi: 10.1016/j.jpedsurg.2017.07.009

Table 2.

Univariate analysis of 16 criteria associated with presence versus absence of HAEC episodes.

16 Criteria Number of
patients (%)
Odds ratio
(95% CI)
P- value
Distended abdomen
 Yes 36 (31.03) 134.07
(27.46–654.53)
<.001
 No 80 (68.97) 1 (Reference)
Diarrhea with explosive stool
 Yes 28 (24.14) 121.50
(15.36–961.06)
<.001
 No 88 (75.86) 1 (Reference)
Diarrhea with foul smelling stool
 Yes 27 (23.28) 110.12
(13.95–869.21)
<.001
 No 89 (76.72) 1 (Reference)
Lethargy*
 Yes 23 (19.83) 168.51
(21.71–21,732.18)
<.001
 No 93 (80.17) 1 (Reference)
Explosive discharge of gas and stool on rectal exam
 Yes 22 (18.97) 68.73
(8.74–540.38)
<.001
 No 94 (81.03) 1 (Reference)
Fever
 Yes 22 (18.97) 68.73
(8.74–540.38)
<.001
 No 94 (81.03) 1 (Reference)
Dilated loops of bowel on AXR
 Yes 18 (15.52) 21.04
(4.53–97.67)
<.001
 No 98 (84.48) 1 (Reference)
Leukocytosis*
 Yes 15 (12.93) 79.95
(10.16–10,330.11)
<.001
 No 101 (87.07) 1 (Reference)
Decreased peripheral perfusion*
 Yes 13 (11.21) 65.07
(8.18–8421.86)
<.001
 No 103 (88.79) 1 (Reference)
Multiple air fluid levels
 Yes 10 (8.62) 19.06
(2.32–156.55)
0.006
 No 106(91.38) 1 (Reference)
Previous history of suspected enterocolitis*
 Yes 9 (7.76) 40.48
(4.89–5273.84)
<.001
 No 107 (92.24) 1 (Reference;
Left shift on complete blood count*
 Yes 9 (7.76) 40.48
(4.89–5273.84)
<.001
 No 107 (92.24) 1 (Reference)
Diarrhea with bloody stool*
 Yes 3 (2.59) 12.70
(1.19–1724.37)
0.034
 No 113 (97.41) 1 (Reference)
Cutoff sign in rectosigmoid region*
 Yes 2 (1.72) 8.85
(0.70–1232.85)
0.096
 No 114(98.28) 1 (Reference)
Sawtooth appearance with irregular mucosal lining*
 Yes 1 (0.86) 5.19
(0.27–764.08)
0.274
 No 115 (99.14) 1 (Reference)
Pneumatosis intestinalis*
 Yes 1 (0.86) 5.19
(0.27–764.08)
0.274
 No 115 (99.14) 1 (Reference)
*

Firth’s penalized maximum likelihood estimation along with profile-likelihood con-fidence interval and p-value from penalized likelihood ratio test [10,11] was reported to reduce bias in the parameter estimates since quasi-complete separation of data points was detected and the maximum likelihood estimate may not exist.