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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Bioessays. 2018 Mar 6;40(4):e1700234. doi: 10.1002/bies.201700234

Figure 1. Diagram illustrating anatomical pathways conveying twitch-related sensory feedback in neonatal rats.

Figure 1.

A twitch of the forelimb is generated in the red nucleus during active sleep. Sensory feedback (or reafference) from the twitch causes a cascade of precisely timed neural responses in sensorimotor structures across the neuraxis, including spinal cord, red nucleus, sensorimotor cortex, and hippocampus. Through repeated activation of these structures, twitches provide a unique opportunity for the synchronization of oscillatory activity. See text for further discussion.