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. Author manuscript; available in PMC: 2019 Jan 4.
Published in final edited form as: Adv Funct Mater. 2017 Nov 8;28(1):1704939. doi: 10.1002/adfm.201704939

Figure 3. Assessment of cell functions and gene expression for PANP-labeled hESC-CMs in vitro.

Figure 3.

(A) Eight parameters regarding calcium handling were comprehensively compared between PANP-labeled cells and unlabeled control cells and all of them showed no significant difference (P > 0.05). (B) Four parameters regarding contractility were compared between PANP-labeled cells and unlabeled control cells, and none of them showed a significant difference (P > 0.05). These results indicate that cell functions of hESC-CMs are minimally affected by PANP labeling. (C) Negative Log-transformed P-values for each gene are plotted as bar graph with threshold (P = 0.05, -log10[0.05] = 1.301) plotted as a straight line. Except the upregulation of GJA5 and HAND1 following PANP labeling, the remaining 30 genes showed no significant differences between control and labelled cells. P < 0.05 stands for significance. N = 17 for each group.