Table 1.
Demographics and clinical features among DMSA, NDMSA, and HCs
| Measure | DMSA | NDMSA | HCs | Statistic |
P-value
|
||
|---|---|---|---|---|---|---|---|
| DMSA vs HCs | NDMSA vs HCs | DMSA vs NDMSA | |||||
|
| |||||||
| Age | 62.36±5.25 | 64.86±9.31 | 64.53±4.16 | F=0.97 | 0.25 | 0.86 | 0.21 |
| Sex (male/female) | 12:17 | 18:11 | 19:15 | F=1.59 | 0.19 | 0.63 | 0.08 |
| Education (years) | 10.21±3.40 | 11.24±3.80 | 11.24±2.09 | F=1.03 | 0.20 | 0.99 | 0.22 |
| Handedness (R/L) | 28:0 | 29:0 | 34:0 | F=0.00 | 1.00 | 1.00 | 1.00 |
| HAMD-17 | 22.54±5.17 | 4.76±1.85 | 0.77±0.85 | F=415.31 | 0.00* | 0.00* | 0.00* |
| MMSE | 27.29±1.49 | 27.24±1.79 | 27.88±1.32 | F=1.75 | 0.13 | 0.10 | 0.91 |
| Dur (years) | 3.93±2.31 | 3.29±1.71 | NA | T=0.52 | NA | NA | 0.95 |
| H-Y | 2.46±0.82 | 2.29±0.59 | NA | T=0.60 | NA | NA | 0.87 |
| UMSARS | 15.01±8.18 | 11.35±7.48 | NA | T=0.89 | NA | NA | 0.40 |
| LED (mg) | 539.29±187.75 | 513.79±229.47 | NA | U=347.5 | NA | NA | 0.34 |
Notes: Values are represented as mean±SD.
*
Means value is less than 0.00; P<0.05 is considered as statistically significant.
Abbreviations: DMSA, MSA patients with depression; Dur, disease duration; HAMD-17, 17-item Hamilton Depression Rating Scale; HC, healthy control; H-Y, Hoehn and Yahr staging scale; LED, levodopa equivalent dose (mg); MMSE, Mini–Mental State Examination; MSA, multiple system atrophy; NA, not applicable; NDMSA, MSA patients without depression; UMSARS, Unified Multiple System Atrophy Rating Scale.