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. 2018 Nov 14;9:2621. doi: 10.3389/fimmu.2018.02621

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Copyright © 2018 Lago, Silva, Lago, Carvalho, Zanette and Castellucci.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative gene expression of miR-361-3p (A), miR-140-3p (B), miR-103a-2-5p (C), and miR-205-3p (D) between CL skin and normal skin samples from the same patient. All values were represented by the equation 2-ΔΔCt of the lesion in relation to the normal skin of each individual. The bars represent the median of the groups. Data were analyzed using the non-parametric Mann–Whitney test as implemented by the GraphPad Prism program. The miR-361-3p and miR-140-3p were significantly more expressed in LC lesions compared to normal skin samples (p = 0.0001 and p < 0.0001, respectively).