Table 4.
Multivariable analysis of risk factors associated with postoperative acute kidney injury after liver transplantation defined by KDIGO criteria.
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Male sex | 0.75 | 0.56–1.02 | 0.063 | |||
| Body mass index | 1.08 | 1.04–1.12 | <0.001 | 1.09 | 1.04–1.13 | <0.001 |
| Hypertension | 0.72 | 0.49–1.06 | 0.097 | |||
| Early postoperative MBP (by decrease of 10 mmHg) | 1.44 | 1.24–1.66 | <0.001 | 1.36 | 1.16–1.59 | <0.001 |
| MELD score | 1.04 | 1.02–1.07 | <0.001 | |||
| Cystatin C GFR (by decrease of 10 ml/min/1.73 m2) | 1.10 | 1.06–1.15 | <0.001 | 1.05 | 1.01–1.10 | 0.016 |
| Albumin | 0.42 | 0.33–0.54 | <0.001 | 0.52 | 0.40–0.68 | <0.001 |
| Hepatitis B cirrhosis | 0.61 | 0.47–0.79 | <0.001 | |||
| Alcoholic cirrhosis | 1.77 | 1.25–2.55 | 0.002 | 1.44 | 0.99–2.12 | 0.062 |
| Donor age | 1.02 | 1.00–1.03 | 0.039 | |||
| Transfused packed red blood cell (by unit) | 1.04 | 1.02–1.05 | <0.001 | 1.02 | 1.00–1.04 | 0.021 |
| Graft-to-recipient weight ratio | 0.50 | 0.30–0.84 | 0.008 | |||
KDIGO – the Kidney Disease: Improving Global Outcomes; OR – odds ratio; CI – confidence interval; MBP – mean arterial blood pressure; MELD – model for end-stage liver disease; GFR – glomerular filtration rate.