Table 1.
Features of the discharged kidney enrolled in the 5 study groups.
| CS (4) | Hyp (4) | PE (4) | PE-Hyp (4) | PE-O2 (4) | p | |
|---|---|---|---|---|---|---|
| Mean donor age | 74±6 | 74±6 | 69±5 | 69±5 | 70±4 | n.s. |
| Mean cold ischemia time | 22.3±2.2 | 22.3±2.2 | 26.8±3.3 | 22.8±1.6 | 26.5±1.4 | n.s. |
| Mean Remuzzi score | 5 | 5 | 6 | 5.5 | 4.5 | n.s. |
| Mean pO2 at T0 | 67±4 | 65±7 | 75±5 | 72±3 | 68±7 | n.s. |
| Mean pO2 at T1 | 176±48 | 282±29* | 106±37 | 366±83* | 710±39* | <0.001* |
| Mean pCO2 at T0 | 7±2.5 | 6.3±2.5 | 6.5±4.4 | 5.3±1.3 | 4.3±0.5 | n.s. |
| Mean pCO2 at T1 | 8.3±3.3 | 12±3.5* | 7±2.5 | 40±19.6* | 4.8±1 | <0.001* |
| Mean lactic acid at T0 | 0.3±0.2 | 0.2±0 | 4.3±5.9 | 0.7±0.8 | 2.2±0.6 | n.s. |
| Mean lactic acid at T1 | 0.5±0.4 | 0.3±0.2 | 12.7±9.9* | 2.1±2.6 | 9.5±5.5* | <0.001* |
| Mean pH at T0 | 6.99±0.05 | 7.03±0.04 | 6.96±0.08 | 6.98±0.01 | 7.04±0.03 | n.s. |
| Mean pH at T1 | 6.96±0.07 | 6.85±0.02 | 6.85±0.08 | 6.80±0.01 | 7±0.21 | n.s. |
CS – static cold storage; Hyp – static cold hyperbaric oxygenation with 1.5 atm; PE – hypothermic perfusion with arterial pressure of 25–30 mmHg; PE-Hyp – hypothermic perfusion in hyperbaric oxygenation with arterial pressure of 25–30 mmHg and with 1.5 atm; PE-O2 – hypothermic oxygenated perfusion with arterial pressure of 25–30 mmHg and with 2–4 L of O2 level maintaining pO2 close to 700 mmHg; T0 – before starting the treatment; T1 – at the end of three hours of treatment. All preservation treatments were performed for three hours at 4°C with 1 L Celsior solution.