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(A–C) Imaging studies demonstrating a left frontal lesion; representative images of hematoxylin & eosin (D) and the indicated immunohistochemical (E–I) stained slides of lesion; (J) Pyrogram of IDH1 gene pyrosequencing (wild-type sequence GACGA corresponding to compliment of nucleotides 397–393 of IDH1 cDNA, c.394C>T; p.R132C mutation).
