Table. Characteristics of Study Participants.
| Characteristic | Study Group | P Valuea | ||
|---|---|---|---|---|
| Sepsis (n = 16) | No Sepsis | |||
| Bacteremia (n = 45) | No Bacteremia (n = 151) | |||
| Age at diagnosis, median (IQR), y | 7.8 (3.8-14.7) | 3.8 (2.5-7.9) | 5.3 (3.4-8.9) | .07b |
| Time to evaluation, median (IQR), yc | 6.9 (6.2- 8.9) | 7.7 (6.6-9.4) | 7.3 (6.1-8.8) | .67b |
| Female, No. (%) | 8 (50.0) | 27 (60.0) | 69 (45.7) | >.99d |
| Race/ethnicity, No. (%) | ||||
| White | 13 (81.2) | 37 (82.2) | 123 (81.4) | .57e |
| Black or other | 3 (18.8) | 8 (17.8) | 28 (18.5) | |
| Final leukemia risk category, No. (%) | ||||
| Low | 10 (62.5) | 31 (68.9) | 81 (53.6) | .80d |
| Standard | 6 (37.5) | 14 (31.1) | 70 (46.4) | |
| Sepsis during treatment, No. (%) | ||||
| Severe sepsisf | 9 (56.2) | NA | NA | NA |
| Urgent interventiong | 7 (43.8) | NA | NA | |
Abbreviations: IQR, interquartile range; NA, not applicable.
a
Describes the difference between participants with sepsis (n = 16) and all others (n = 196).
b
Calculated using the Mann-Whitney test.
c
Indicates time to performance-based neurocognitive assessment since diagnosis of acute lymphoblastic leukemia.
d
Calculated using the Fisher exact test.
e
Calculated using the χ2 test.
f
Defined by Goldstein et al.5
g
Defined by Wolf et al.4