Table 2.

Complement profile and results of microplate/WB tests for C3NeF IgGs in the 26 patients with C3G or primary IC-MPGN.

LPV, likely pathogenetic variants; Ab, antibodies.

^*Values measured at the time of sample collection of IgG isolation;

^$serum C3 normal range 90–180 mg/dl; °limit of C3NeF positivity in the hemolytic assay (HA);

^∧upper limit of normal plasma sC5b-9 range. WB, western blot; TM, thrombomodulin.

^#IgGs were added during C3 convertase formation;

^§IgGs were added during decay. Results are the mean of 3 experiments for each patient. n.a, sample not available.