Table 3B.

Prevalence of patients with C3NeF IgGs with properdin (P) independent (CSA+/PCSA+) or dependent (CSA–/PCSA+) C3 convertase stabilizing activity against spontaneous (s) or FH-mediated (FH) decay among histology groups or clusters.

		C3GN	DDD	IC-MPGN	p	Cluster 1	Cluster 2	Cluster 3	p
Spontaneous	sCSA−/sPCSA−	0%	0%	8%	1.000	0%	13%	0%	0.308
	sCSA−/sPCSA+	75%	33%	69%	0.239	78%	75%	22%	0.040
	sCSA+/sPCSA+	25%	67%	23%	0.115	22%	13%	78%	0.017
FH-mediated	FH-CSA−/FH-PCSA−	0%	22%	15%	1,000	11%	25%	11%	0.653
	FH-CSA−/FH-PCSA+	75%	11%	62%	0.026	67%	63%	11%	0.042
	FH-CSA+/FH-PCSA+	25%	67%	23%	0.115	22%	13%	78%	0.017

Bold characters indicate statistically significant values.