Table 1. Clinical and Demographic Characteristics of the Study Population.
| Characteristic | Patients, No. (%) |
|---|---|
| Age, mean (SD), y | 63.0 (11.9) |
| Male sex | 118 (79.7) |
| White race | 143 (96.6) |
| Smoker at baseline | 34 (23.0) |
| Study site | |
| UNMC | 68 (45.9) |
| NMH | 80 (54.1) |
| Prognostic stage (clinical) | |
| II | 35 (23.6) |
| III or IV | 113 (76.4) |
| Initial treatment | |
| Surgery (not biopsy) | 81 (54.7) |
| Radiotherapy with or without chemotherapy | 67 (45.3) |
| Cancer site | |
| Pharynx | 49 (33.1) |
| Oral | 65 (43.9) |
| Other | 34 (23.0) |
| Intervention | |
| Escitalopram oxalate | 74 (50.0) |
| Placebo | 74 (50.0) |
Abbreviations: NMH, Nebraska Methodist Hospital; UNMC, University of Nebraska Medical Center.