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. 2019 Jan 2;3:135. Originally published 2018 Oct 29. [Version 2] doi: 10.12688/wellcomeopenres.14867.2

PMC6248268.1; 2018 Oct 29
PMC6248268.2; 2019 Jan 2

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Copyright: © 2019 Ashwin H et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 11. — A and B. Murine whole blood data from day 36 p.i. was re-analysed with a cut off of log2FC= 1.5 to make comparable with the human data presented in 39. Venn diagram indicates a minimal overlap between DE genes that are up regulated ( A) and down-regulated ( B) during infection. C and D. STRING analysis of the common up-regulated ( C) and down-regulated ( D) genes. E and F. Most significant (by FDR) GO terms and Kegg pathways associated with mouse and human specific up-regulated ( E) and down-regulated ( F) genes, generated by STRING.