Table 1.
Complication | Definition | Timing |
---|---|---|
Significant arrhythmias | ||
• Bradyarrhythmia | A decrease in HR ≥15% of the pre-reperfusion level | Immediate reperfusion period |
• New-onset arrhythmias | Hemodynamically significant arrhythmias (hyperkalemia-related and/or others) | Immediate reperfusion period |
• Cardiac arrest | Loss of spontaneous heart beat and requires cardiac massage | Immediate reperfusion period |
Refractory hypotension | ||
• Severe hypotension | A drop in SAP unresponsive to an accumulated bolus of 1 μg/kg epinephrine | Immediate reperfusion period |
• Persistent hypotension | A drop in SAP ≥30% of the pre-reperfusion level and lasting ≥5 min | Immediate reperfusion period |
• New-onset vasoplegic syndrome | NE ≥0.5 μg/kg/min, SAP <30–50% of baseline, high CO, and low SVR | Late reperfusion period |
• Prolonged vasopressor treatment | Refractory hypotension requiring prolonged NE infusion to ICU | At the end of surgery |
Presence of one or more of the 7 factors indicates PRS. CO – cardiac output; HR – heart rate; NE – norepinephrine; ICU – intensive care unit; PRS – postreperfusion syndrome; SAP – systolic arterial pressure; SVR – systemic vascular resistance.