Table 3.
Postreperfusion complications and postoperative outcomes.
| Variables | PRS group (n=26) | Non-PRS group (n=49) | P-value |
|---|---|---|---|
| During the immediate reperfusion period | |||
| Dose of epinephrine (μg/kg) | 0.74 (0.65–1.16) | 0.17 (0.08–0.28) | <0.001 |
| K at 5 min of reperfusion (mmol/L) | 4.0±0.7 | 3.2±0.8 | <0.001 |
| GLU at 5 min of reperfusion (mmol/L) | 10.9±3.9 | 11.6±3.5 | 0.422 |
| LAC at 5 min of reperfusion (mmol/L) | 5.4±2.4 | 4.4±1.4 | 0.056 |
| During the late reperfusion period | |||
| Number requiring NE infusion (%)a | 20 (80.0%) | 5 (10.2%) | <0.001 |
| Dose of NE (μg/kg/min)a | 0.30 (0.20–0.45) | 0.00 (0.00–0.00) | <0.001 |
| New-onset VS (%)a | 9 (36.0%) | 0 (0.0%) | <0.001 |
| At the end of surgery | |||
| Number requiring NE infusion (%)a | 2 (8.0%) | 0 (0.0%) | 0.111 |
| Duration of anesthesia (min)a | 468±89 | 453±90 | 0.509 |
| Duration of surgery (min)a | 375 (330–435) | 360 (330–405) | 0.586 |
| Blood loss (ml/kg)a | 32.9 (18.2–64.1) | 21.3 (12.0–40.9) | 0.078 |
| RBC transfusion (ml/kg)a | 34.8 (21.9–66.5) | 26.7 (13.3–51.0) | 0.097 |
| FFP transfusion (ml/kg)a | 0 (0–20) | 0 (0–25) | 0.786 |
| During the postoperative period | |||
| Peak ALT (IU/L)a | 1487 (848–2210) | 497 (287–735) | <0.001 |
| Peak AST (IU/L)a | 4179 (2828–5818) | 1167 (715–1674) | <0.001 |
| Peak LDH (IU/L)a | 3826 (2836–5946) | 1446 (1073–2189) | <0.001 |
| Peak GGT (IU/L)a | 200 (103–353) | 249 (133–372) | 0.560 |
| Peak TB (umol/L)a | 118.9±95.3 | 122.8±79.8 | 0.853 |
| EAD (%) | 19 (73.1%) | 9 (18.4%) | <0.001 |
| PNF (%) | 3 (11.5%) | 0 (0.0%) | 0.039 |
| Graft loss within 1 month (%) | 4 (15.4%) | 0 (0.0%) | 0.012 |
| AKI (%)a | 4 (16.0%) | 4 (6.1%) | 0.217 |
| Ventilation time (hours)a | 2.4 (1.8–6.3) | 2.5 (1.6–3.9) | 0.513 |
| ICU stay (days)a | 4.3 (2.9–5.8) | 3.5 (2.8–4.5) | 0.205 |
| Hospital stay (days)a | 30.5 (22.0–49.8) | 21.0 (17.5–25.5) | 0.007 |
| In-hospital death (%)a | 1 (4.0%) | 0 (0.0%) | 0.338 |
a
The patient died during the operation was excluded from the final analysis in the PRS group.
AKI – acute kidney injury; ALT – alanine aminotransferase; AST – aspartate aminotransferase; EAD – early allograft dysfunction; FFP – fresh frozen plasma; GGT – gamma-glutamyl transpeptidase; GLU – serum glucose concentration; ICU – intensive care unit; K – serum potassium concentration; LAC – serum lactate concentration; LDH – lactic dehydrogenase; NE – norepinephrine; PNF – primary nonfunction; PRS – postreperfusion syndrome; RBC – red blood cell; TB – total bilirubin; VS – vasoplegic syndrome.