TABLE 1.
Non-ECT groupb (N=969,277) |
ECT group (N=2,471) |
Effect size | ||||
---|---|---|---|---|---|---|
Variable | N | % | N | % | Risk ratio | Cohen’s d |
Demographic characteristic | ||||||
Male | 315,132 | 32.6 | 806 | 32.6 | 1.00 | |
Age (years), M±SD | 42.96±13.6 | 46.36±12.4 | .27 | |||
Urban area resident | 850,347 | 87.7 | 2,183 | 88.3 | 1.01 | |
Comorbid medical condition | ||||||
Seizures | 12,794 | 1.3 | 77 | 3.1 | 2.36 | |
Insomnia | 43,230 | 4.5 | 170 | 6.9 | 1.54 | |
Myocardial infarction | 4,846 | .5 | 17 | .7 | 1.38 | |
Congestive heart failure | 8,917 | ,9 | 32 | 1.3 | 1.41 | |
Peripheral vascular disease | 14,248 | 1.5 | 65 | 2.6 | 1.79 | |
Cerebrovascular accident | 22,972 | 2.4 | 107 | 4.3 | 1.83 | |
Chronic obstructive airway disease | 99,351 | 10.3 | 326 | 13.2 | 1.29 | |
Hepatic disease | 30,629 | 3.2 | 105 | 4.3 | 1.34 | |
Diabetes mellitus | 92,760 | 9.6 | 334 | 13.5 | 1.41 | |
Renal disease | 12,698 | 1.3 | 67 | 2.7 | 2.06 | |
Cancer | 32,083 | 3.3 | 110 | 4.5 | 1.36 | |
Any pain diagnosis | 228,652 | 23.6 | 655 | 26.5 | 1.12 | |
Musculoskeletal pain | 346,517 | 35.8 | 1,119 | 45.3 | 1.27 | |
Charlson Comorbidity Index (M±SD)c | .50±1.18 | .68±1.26 | .15 | |||
Psychiatric diagnosis | ||||||
Other depression (dysthymia) | 270,428 | 27.9 | 1,986 | 80.4 | 2.88 | |
Posttraumatic stress disorder | 41,194 | 4.3 | 285 | 11.5 | 2.71 | |
Anxiety disorder | 380,538 | 39.3 | 1,595 | 64.6 | 1.64 | |
Adjustment disorder | 85,490 | 8.8 | 237 | 9.6 | 1.09 | |
Personality disorders | 14,539 | 1.5 | 273 | 11.1 | 7.37 | |
Schizophrenia | 13,279 | 1.4 | 283 | 11.5 | 8.33 | |
Other psychiatric diagnosis | 30,435 | 3.1 | 443 | 17.9 | 5.70 | |
Alcohol dependence | 44,296 | 4.6 | 240 | 9.7 | 2.12 | |
Cocaine use disorder | 2,035 | .2 | 7 | .3 | 1.33 | |
Cannabis use disorder | 5,525 | .6 | 17 | .7 | 1.21 | |
Sedative use disorder | 4,071 | .4 | 28 | 1.1 | 2.72 | |
Amphetamine use disorder | 1,939 | .2 | 5 | .2 | 1.03 | |
Hallucinogen use disorder | 194 | 0 | 0 | – | 0 | |
Any substance use disorder | 86,444 | 8.9 | 435 | 17.6 | 1.97 | |
Service use | ||||||
Any mental health inpatient treatment | 90,530 | 9.3 | 1,451 | 58.7 | 6.29 | |
Emergency room visits (M±SD) | .55±1.69 | 1.02±2.81 | .20 | |||
Medical and surgical visits (M±SD) | 11.78±14.66 | 14.60±15.32 | .19 | |||
All outpatient visits (M±SD) | 22.61±21.16 | 51.31±32.11 | 1.06 | |||
Psychiatric or substance use outpatient visits (M±SD) |
10.83±13.48 | 36.71±25.39 | 1.27 | |||
Psychotropic medication prescriptions (M±SD) |
||||||
Antidepressant | 3.70±5.20 | 7.06±7.43 | .52 | |||
Antipsychotic | .89±2.81 | 4.13±6.05 | .69 | |||
Anxiolytic, sedative, or hypnotic | 2.36±4.76 | 5.38±6.69 | .52 | |||
Stimulant | .57±2.35 | .75±2.49 | .07 | |||
Lithium | .18±1.24 | .94±2.66 | .37 | |||
Anticonvulsant or mood stabilizer | 1.12±3.11 | 2.28±4.09 | .32 | |||
All psychotropics (M±SD) | 8.82±11.56 | 20.54±18.08 | .77 | |||
Proportion receiving psychotropic prescriptions |
||||||
Antidepressant prescriptions | 515,752 | 53.2 | 1,716 | 69.5 | 1.31 | |
Antipsychotic prescriptions | 153,921 | 15.9 | 1,405 | 56.9 | 3.58 | |
Anxiolytic, sedative, and hypnotic prescriptions |
354,174 | 36.5 | 1,530 | 61.9 | 1.69 | |
Stimulant prescriptions | 82,873 | 8.6 | 347 | 14.0 | 1.64 | |
Lithium | 31,792 | 3.3 | 489 | 19.8 | 6.03 | |
Anticonvulsant and mood stabilizer | 184,744 | 19.1 | 946 | 38.3 | 2.01 | |
All psychotropics | 635,846 | 65.7 | 1,911 | 77.3 | 1.18 | |
Proportion receiving psychotherapy | ||||||
Psychotherapy as outpatient | 540,178 | 55.7 | 1,872 | 75.8 | 1.36 | |
Psychotherapy as inpatient | 6,300 | .7 | 191 | 7.7 | 11.89 | |
Family psychotherapy (outpatient) | 38,674 | 4.0 | 209 | 8.5 | 2.12 | |
Group psychotherapy (outpatient) | 26,558 | 2.7 | 347 | 14.0 | 5.12 | |
Number of psychotherapy visits (M±SD) | ||||||
Psychotherapy, outpatient | 5.74±10.70 | 12.62±16.51 | .49 | |||
Psychotherapy, inpatient | .02±.44 | .49±3.89 | .17 | |||
Family psychotherapy, outpatient | .19±1.79 | .32±2.18 | .06 | |||
Group psychotherapy, outpatient | .26±2.55 | 1.49±5.82 | .27 |
ECT, electroconvulsive therapy
The non-ECT group comprised those in the MarketScan database with a diagnosis of major depressive disorder or bipolar disorder who did not receive ECT.
Possible scores range from 0 upward, with no theoretical upper limit; higher values indicate a greater number of and more severe medical comorbidities.