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Analysis of specificity of dimeric R1.2 constructs against mIgM negative SKLY16 knockout cells. Evaluation of negative mIgM in CRISPR/CAS9 SKLY-16 knockout cells against SKLY16 wild type and analysis of binding of dimeric aptamer constructs to SKLY-16 knockout and wild-type (A). Overall conclusion from three independent binding studies against knockout SKLY-16 cells (B).
