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. 2017 Nov 8;97(6):822–834. doi: 10.1093/biolre/iox143

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© The Author(s) 2017. Published by Oxford University Press on behalf of Society for the Study of Reproduction. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

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Figure 4. — Med12^fl/fl Amhr2-Cre uterine anatomy and histology. (A) Gross morphology of 12-week-old female mouse reproductive tract. The Med12^fl/fl (control mice) display normal reproductive tract. In comparison to the controls, Med12^fl/fl Amhr2-Cre reproductive tract is atrophic. Scale bar = 1cm. (B) Twelve-week-old uterine weight is significantly decreased in Med12^fl/fl Amhr2-Cre as compared to Med12^fl/fl and Med12^fl/+ Amhr2-Cre group (n = 7). Data are presented as mean ± SEM. ^*^*P < 0.01. (C–H) Hematoxylin and eosin staining of uteri from 12-week-old Med12^fl/fl, Med12^fl/+ Amhr2-Cre and Med12^fl/fl Amhr2-Cre mice synchronized with PMSG and hCG. Note the atrophic uteri of Med12^fl/fl Amhr2-Cre female. EM, endometrium; MY, myometrium. Scale bars = 100 μm.