Table 2.
Cortical depth-dependent reduction of cortical myelin between hand and face (in particular lower face, lip, tongue) representations using defined paths based on individual cortical folding patterns
| Layer | Primary motor cortex | Primary somatosensory cortex | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Hand | Border | Face | Hand | Border | Face | |||||
| 1 (D) | 1640.8 ± 10.9 | 1679.2 ± 25.6 | 1691.1 ± 24.6 | 1676.1 ± 17.9 | 1680.8 ± 25.5 | 1705.3 ± 30.3 | ||||
| P = 0.24 | P = 0.70 | P = 0.90 | P = 0.63 | |||||||
| 2 (D) | 1662.4 ± 13.4 | 1721.6 ± 36.7 | 1701.7 ± 30.1 | 1697.2 ± 19.4 | 1708.5 ± 23.3 | 1728.9 ± 31.7 | ||||
| P = 0.18 | P = 0.72 | P = 0.76 | P = 0.65 | |||||||
| 3 (D) | 1670.6 ± 15.6 | 1756.3 ± 46.7 | 1773.8 ± 62.4 | 1711.8 ± 21.2 | 1740.0 ± 24.2 | 1755.2 ± 35.0 | ||||
| P = 0.13 | P = 0.74 | P = 0.47 | P = 0.72 | |||||||
| 4 (D) | 1669.9 ± 16.1 | 1815.0 ± 82.6 | 1758.7 ± 47.2 | 1715.4 ± 22.9 | 1770.6 ± 27.4 | 1781.4 ± 40.5 | ||||
| P = 0.12 | P = 0.46 | P = 0.22 | P = 0.81 | |||||||
| 5 (IM) | 1663.9 ± 14.3 | 1848.4 ± 94.3 | 1778.0 ± 52.2 | 1716.1 ± 25.9 | 1794.2 ± 31.6 | 1804.0 ± 47.6 | ||||
| P = 0.08 | P = 0.38 | P = 0.12 | P = 0.85 | |||||||
| 6 (IM) | 1657.1 ± 13.2 | 1869.3 ± 90.45 | 1762.2 ± 32.9 | 1718.1 ± 29.5 | 1812.4 ± 35.4 | 1829.8 ± 58.8 | ||||
| P = 0.04* | P = 0.31 | P = 0.08 | P = 0.78 | |||||||
| 7 (IM) | 1658.7 ± 11.8 | 1904.8 ± 100.4 | 1790.0 ± 36.3 | 1722.1 ± 33.1 | 1827.0 ± 39.4 | 1857.2 ± 71.0 | ||||
| P = 0.03* | P = 0.29 | P = 0.08 | P = 0.68 | |||||||
| 8 (IM) | 1672.2 ± 11.8 | 1944.5 ± 119.2 | 1782.9 ± 37.3 | 1725.9 ± 36.3 | 1844.8 ± 41.0 | 1883.4 ± 81.7 | ||||
| P = 0.04* | P = 0.28 | P = 0.07 | P = 0.67 | |||||||
| 9 (OM) | 1697.7 ± 12.9 | 1990.3 ± 143.3 | 1785.9 ± 43.7 | 1737.9 ± 37.4 | 1872.3 ± 37.1 | 1907.6 ± 89.9 | ||||
| P = 0.07 | P = 0.26 | P = 0.05* | P = 0.72 | |||||||
| 10 (OM) | 1729.7 ± 16.6 | 2029.7 ± 157.9 | 1798.1 ± 49.8 | 1769.4 ± 35.7 | 1908.4 ± 29.3 | 1937.6 ± 94.4 | ||||
| P = 0.09 | P = 0.25 | P = 0.04* | P = 0.79 | |||||||
| 11 (OM) | 1762.0 ± 23.9 | 2068.7 ± 165.7 | 1810.0 ± 51.5 | 1808.7 ± 37.7 | 1955.1 ± 31.2 | 1969.8 ± 99.7 | ||||
| P = 0.09 | P = 0.22 | P = 0.05* | P = 0.91 | |||||||
| 12 (OM) | 1801.1 ± 28.2 | 2116.9 ± 170.9 | 1829.8 ± 43.4 | 1856.3 ± 42.9 | 2012.3 ± 45.5 | 2005.1 ± 102.7 | ||||
| P = 0.09 | P = 0.16 | P = 0.08 | P = 0.96 | |||||||
| 13 (S) | 1840.4 ± 32.1 | 2157.0 ± 145.5 | 1875.8 ± 41.0 | 1917.4 ± 50.7 | 2081.8 ± 63.8 | 2051.8 ± 101.3 | ||||
| P = 0.05* | P = 0.11 | P = 0.13 | P = 0.85 | |||||||
| 14 (S) | 18823.3 ± 33.9 | 2217.2 ± 116.9 | 1942.8 ± 51.2 | 1996.9 ± 59.4 | 2150.1 ± 71.4 | 2106.3 ± 97.1 | ||||
| P = 0.02* | P = 0.07 | P = 0.20 | P = 0.80 | |||||||
| 15 (S) | 1941.9 ± 36.2 | 2318.3 ± 117.2 | 1988.3 ± 48.4 | 2098.2 ± 64.7 | 2221.7 ± 66.0 | 2185.6 ± 94.7 | ||||
| P = 0.02* | P = 0.04* | P = 0.29 | P = 0.82 | |||||||
| 16 (S) | 2055.2 ± 44.8 | 2451.7 ± 127.6 | 2080.6 ± 57.1 | 2219.0 ± 67.9 | 2312.2 ± 60.1 | 2294.4 ± 93.3 | ||||
| P = 0.04* | P = 0.04* | P = 0.40 | P = 0.89 | |||||||
Notes: T1 values (ms) extracted from different cortical depths and brain areas (primary motor cortex and primary somatosensory cortex) are shown as mean ± SEM. Values were extracted from functionally defined hand representations, functionally defined face representations, and the hand–face intersection point (averaged over N = 7 participants). Note that high values correspond to low cortical myelin. Significant comparisons (P < 0.05) are marked with a star and are printed in bold. D, deep cortical layers; IM, inner middle cortical layers; OM, outer middle cortical layers; S, superficial cortical layers.