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The human herpes virus 8–positive (HHV8+) plasmablasts are variably positive for CD20 (A [SH2015-264]) and CD79a (B [SH2015-264]). The interfollicular CD138+ plasma cells are often numerous (C [SH2015-228]) but in contrast to the HHV8+ plasmablasts are polytypic based on cytoplasmic κ (D [SH2015-264]) and λ (E [SH2015-264]) light chain expression (courtesy of Drs Monaghan, Kumar, and Luu and Drs Oak, Tan, and Fong).
