Table 2.
Rates and Standardized Incidence Ratios of Cancers in Older Persons Living With Human Immunodeficiency Virus Infection (Age ≥50 Years)
| Cancers | Observed Cases, No. | Expected Cases, No. | IR per 100000 PY | SIR (95% CI) |
|---|---|---|---|---|
| All cancers | 10371 | 8929 | 1117.3 | 1.16 (1.14–1.18) |
| ADCs | ||||
| Kaposi sarcoma | 338 | 3.3 | 36.4 | 103.34 (92.62–114.97) |
| NHL | 1222 | 401.2 | 131.7 | 3.05 (2.88–3.22) |
| Diffuse large B cell | 674 | 110.0 | 72.6 | 6.12 (5.67–6.61) |
| Burkitt | 103 | 7.5 | 11.1 | 13.75 (11.23–16.68) |
| CNS | 74 | 8.1 | 8.0 | 47.39 (37.21–59.49) |
| Other/unspecified | 371 | 282.1 | 39.9 | 1.32 (1.18–1.46) |
| Cervical cancer | 87 | 43.0 | 36.5 | 2.02(1.62–2.49) |
| NADCs | ||||
| Anal | 524 | 37.4 | 56.5 | 14.00 (12.82–15.25) |
| Lung | 1725 | 1012 | 185.8 | 1.71 (1.63–1.79) |
| Liver | 805 | 276.4 | 86.7 | 2.91 (2.71–3.12) |
| Hodgkin lymphoma | 253 | 33.3 | 27.3 | 7.61 (6.70–8.60) |
| Oral cavity/pharynx | 461 | 278.4 | 49.7 | 1.66 (1.51–1.81) |
| Female breast | 329 | 542.0 | 137.9 | 0.61 (.54–.68) |
| Prostate | 1341 | 2829 | 194.5 | 0.47 (.45–.50) |
| Colon (excluding rectum) | 360 | 571.3 | 38.8 | 0.63 (.57–.70) |
| Other cancers | 2926 | 5731 | 315.2 | 1.01 (.97–1.05) |
Abbreviations: ADCs, AIDS-defining cancers; CI, confidence intervals; CNS, central nervous system; IR, incidence rate; NADCs, non–AIDS-defining cancers; NHL, non-Hodgkin lymphoma; PY, person-years; SIR, standardized incidence ratio.