Table 1.
Characteristic | Total, N = 52 | Spontaneously Cleared, N = 14 (%) | Persistently Infected, N = 38 (%) | P Value |
---|---|---|---|---|
Number (n = 52) | 14/52 (26.9) | 38/52 (73.1) | ||
Mean age, y (standard deviation) | 31.7 (5.2) | 30.7 (5.2) | 32.0 (5.3) | .43 |
Interleukin-28B gene (rs12979860) | ||||
CC allele | 28/52 (53.8) | 10/28 (35.7) | 18/28 (64.3) | .21 |
CT allele | 17/52 (32.7) | 2/17 (11.8) | 15/17 (88.2) | |
TT allele | 7/52 (13.5) | 2/7 (28.6) | 5/7 (71.4) | |
Maternal HCV viral load at baseline | ||||
Median (interquartile range) | 80450 (4789891) | 68500 (4789093) | 100200 (3899891) | .43 |
Primigravida | 4/52 (7.7) | 0/14 (0.0) | 4/38 (10.5) | .56 |
Multigravida | ||||
History of preterm births | 1/52 (1.9) | 0/14 (0.0) | 1/38 (2.6) | 1.00 |
History of abortion | 17/52 (32.7) | 6/14 (42.9) | 11/38 (28.9) | .20 |
Number of full-term births | 47/52 (90.4) | 13/14 (92.9) | 34/38 (89.5) | .43 |
Have children who are currently alive | 47/52 (90.4) | 13/14 (92.9) | 34/38 (89.5) | .51 |
HCV risk factors | ||||
Working in health sector | 3/52 (5.8) | 0/14 (0.0)a | 3/38 (7.9) | 1.00 |
History of jaundice | 0/52 (0.0)a | 0/14 (0.0)a | 0/38 (0.0)a | N/A |
History of liver disease | 3/52 (5.8) | 3/14 (21.4) | 0/38 (0.0) | .02 |
History of surgery | 34/52 (65.4) | 11/14 (78.6) | 23/38 (60.5) | .33 |
History of blood transfusion | 4/52 (7.7) | 1/14 (7.1) | 3/38 (7.9) | 1.00 |
History of needle-stick injury | 1/52 (1.9) | 1/14 (7.1) | 0/38 (0.0)a | .27 |
History of tattoos | 0/52 (0.0)a | 0/14 (0.0)a | 0/38 (0.0)a | N/A |
History of endoscopy | 1/52 (1.9) | 1/14 (7.1) | 0/38 (0.0)a | .27 |
History of renal dialysis | 0/52 (0.0)a | 0/14 (0.0)a | 0/38 (0.0)a | N/A |
History of dental treatment | 42/52 (80.8) | 13/14 (92.9) | 29/38 (76.3) | .25 |
History of intravenous injection with needle sharing | 0/52 (0.0)a | 0/14 (0.0)a | 0/38 (0.0)a | N/A |
Abbreviation: HCV, hepatitis C virus.
aToo sparse for inference.