Skip to main content
. 2017 May 10;65(6):999–1005. doi: 10.1093/cid/cix445

Table 1.

Unadjusted Comparison of Postpartum Women Tested for the Interleukin-28B Gene Allele Who Spontaneously Cleared Their Chronic Hepatitis C Virus Infection and Those Who Remained Persistently Infected

Characteristic Total, N = 52 Spontaneously Cleared, N = 14 (%) Persistently Infected, N = 38 (%) P Value
Number (n = 52) 14/52 (26.9) 38/52 (73.1)
Mean age, y (standard deviation) 31.7 (5.2) 30.7 (5.2) 32.0 (5.3) .43
Interleukin-28B gene (rs12979860)
 CC allele 28/52 (53.8) 10/28 (35.7) 18/28 (64.3) .21
 CT allele 17/52 (32.7) 2/17 (11.8) 15/17 (88.2)
 TT allele 7/52 (13.5) 2/7 (28.6) 5/7 (71.4)
Maternal HCV viral load at baseline
 Median (interquartile range) 80450 (4789891) 68500 (4789093) 100200 (3899891) .43
Primigravida 4/52 (7.7) 0/14 (0.0) 4/38 (10.5) .56
Multigravida
 History of preterm births 1/52 (1.9) 0/14 (0.0) 1/38 (2.6) 1.00
 History of abortion 17/52 (32.7) 6/14 (42.9) 11/38 (28.9) .20
 Number of full-term births 47/52 (90.4) 13/14 (92.9) 34/38 (89.5) .43
 Have children who are currently alive 47/52 (90.4) 13/14 (92.9) 34/38 (89.5) .51
HCV risk factors
 Working in health sector 3/52 (5.8) 0/14 (0.0)a 3/38 (7.9) 1.00
 History of jaundice 0/52 (0.0)a 0/14 (0.0)a 0/38 (0.0)a N/A
 History of liver disease 3/52 (5.8) 3/14 (21.4) 0/38 (0.0) .02
 History of surgery 34/52 (65.4) 11/14 (78.6) 23/38 (60.5) .33
 History of blood transfusion 4/52 (7.7) 1/14 (7.1) 3/38 (7.9) 1.00
 History of needle-stick injury 1/52 (1.9) 1/14 (7.1) 0/38 (0.0)a .27
 History of tattoos 0/52 (0.0)a 0/14 (0.0)a 0/38 (0.0)a N/A
 History of endoscopy 1/52 (1.9) 1/14 (7.1) 0/38 (0.0)a .27
 History of renal dialysis 0/52 (0.0)a 0/14 (0.0)a 0/38 (0.0)a N/A
 History of dental treatment 42/52 (80.8) 13/14 (92.9) 29/38 (76.3) .25
 History of intravenous injection with needle sharing 0/52 (0.0)a 0/14 (0.0)a 0/38 (0.0)a N/A

Abbreviation: HCV, hepatitis C virus.

aToo sparse for inference.